Comprehensive Biophysics

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Edward Egelman received a BA in physics and a PhD in biophysics from Brandeis University. He was a postdoctoral fellow at the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK, and then an assistant professor at Yale University. He was an associate and full professor at the University of Minnesota Medical School, and then moved to the University of Virginia in 1999 where he is a professor of biochemistry and molecular genetics. He is currently editor-in-chief of Biophysical Journal. He has been elected a fellow of the Biophysical Society and of the American Academy of Microbiology. His research focuses on the structure and function of macromolecular complexes, mainly using electron cryo-microscopy and computational image analysis. He has spent many years studying the structure of F-actin, as well as helical nucleoprotein complexes formed by recombination proteins (such as the bacterial RecA and the eukaryotic Rad51) on DNA.
X-ray crystallography
NMR Spectroscopy
Electron microscopy
Mass spectrometry
Ultrafast spectroscopic techniques
EPR and Other electron spectroscopies
Fast flow
Other spectroscopy - UV-Vis, CD, Raman, vibrational CD
Elucidating cellular structures
Protein Folding
Globular Proteins
Nucleic Acid Folding
General Theoretical Considerations
Non-Muscle Motility
Nucleic Acid Motors
Lipid Bilayers
Membrane Proteins
Protein Interactions with Membranes
Membrane Conformational Transitions
Membrane Dynamics
Lipid Bilayers
Molecular Modeling approaches to understand mechanisms in Voltage-Gated Channels
Connexin Channels
Structure-function correlates of Glutamate-Gated ion channels
TRP channels
Structure and mechanisms in chloride channels
Biophysics of Ceramide Channels
Proton channels
Structure-function correlates of voltage-gated potassium channels
Store-operated Calcium Channels
Bacterial Toxin channels
Viral channels
Structure-Function Correlates in Plant Channels | Plant channels
Biophysics of cell-matrix adhesion
Biophysics of selectin-mediated cell-cell adhesions
Biophysics of cadherin-mediated cell-cell adhesion
Biophysics of cell division
Biophysics of bacterial cell growth and division
Biophysics of three-dimensional cell motility
Biophysics of molecular cell mechanics
Biophysics of nuclear organization and dynamics
Cell-extracellular matrix mechanobiology in cancer
Biophysics of cell motility
Biophysics of cell developmental processes
Biophysics of bacterial organization
Structure-function relationships in P-type ATPases
Rotational catalysis by the ATP synthase
Bacterial rotary flagellar motor
Electron transport chains
Light capture - photos
Photosystems of bacteria and plants
A B C Transporters
The mitochondrial family of transport proteins
Bacteriorhodopsin and Related Proteins
Theory of transport processes
Structure function relationships in membrane transport prtotreins of the MFS and leu-T families (approximate)
In silico approches to structure and function of cell components and their aggregates
Simulations of molecular machines
In silico approches to structure and function of cell components and their assemblies
Modeling of interaction networks in the cell
Mathematical modeling of complex biological systems

Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap.

Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge.

  • Biophysical research today encompasses many areas of biology. These studies do not necessarily share a unique identifying factor. This work unites the different areas of research and allows users, regardless of their background, to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding
  • The field of biophysics counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Biophysics fills this vacuum, being a definitive work on biophysics. It will help users apply context to the diverse journal literature offering, and aid them in identifying areas for further research
  • Chief Editor Edward Egelman (E-I-C, Biophysical Journal) has assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource

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