Alejandro C. Olivieri was born in Rosario, Argentina, on July 28, 1958. He is a member of the Institute of Chemistry of Rosario, and professor of the Department of Analytical Chemistry of the National University of Rosario. Degree in Industrial Chemistry (Catholic Faculty of Chemistry and Engineering, 1982), Doctor (Faculty of Biochemical and Pharmaceutical Sciences, University of Rosario, 1986), fellow of the National Council for Scientific and Technical Research (CONICET). About 250 publications, books and book chapters. John Simon Guggenheim Memorial Foundation Fellow (2001-2002). Konex Platinum Award (Konex Foundation, Argentina, 2013) for his contributions to analytical chemistry. Current interest: chemometrics in analytical chemistry.Graciela M. Escandar was born in Rosario city, Argentina. She obtained her B.Sc. in Biochemistry in 1983 and her Ph.D. in 1992, both from the Faculty of Biochemical and Pharmaceutical Sciences, University of Rosario, where she was full professor in the Department of Analytical Chemistry, and fellow of the National Research Council of Argentina (CONICET). She has published about 130 scientific papers in well-known international journals, reviews, books and book chapters, and supervised seven Ph.D. Theses. Her research focuses on the development of new green methodologies based on molecular luminescence in organized media and solid-phase for the determination of analytes of environmental and pharmaceutical interest.

Foreword1. Calibration Scenarios2. Data Properties3. Experimental Three-Way/Second-Order Data4. The Mvc2 Software5. Parallel Factor Analysis: Trilinear Data6. Analytical Figures of Merit7. Parallel Factor Analysis: Non-Trilinear Data of Type 18. Multivariate Curve Resolution-Alternating Least-Squares9. Partial Least-Squares with Residual Bilinearization10. Three-Way/Second-Order Standard Addition11. Third-Order/Four-Way Calibration and Beyond12. Application Example: Parafac13. Application Example: Mcr-Als14. Application Example: U-Pls/Rbl15. Solutions to Homework