Almost exactly ten years ago, two young physicians joined me at the University of Oklahoma for the study of dermatopathology: Stephen C. Somach, a brilliant dermatologist-scholar from Cleveland, who was also a highly accomplished cellist, and Michael B. Morgan, an effervescent, newly minted pathologist from Florida, who was brimming with energy, curiosity, and zeal and was also spo- ing water skiis and a red Porsche! Bruce R. Smoller, whose impressive erudition is universally acknowledged, I met during a Residency Review committee visit to Stanford some ?fteen years ago. Each of these men has made original cont- butions to the dermatopathology literature as well as to patient care in the cli- cal setting. Their publications have broadened our understanding of the biologic behavior of pigmented lesions, cutaneous lymphomas, vascular lesions, and soft tissue tumors. It is indeed a pleasure to welcome their volume, Deadly Der- tologic Diseases, a unique and stimulating outcome of their enthusiastic collaboration. Deadly Dermatologic Diseases discusses a wide variety of entities–neoplastic, vascular, infectious, metabolic–each of which may eventuate in death of the patient. In addition, numerous tumors and dermatoses frequently associated with internal malignancies are reviewed. High-quality histologic photomic- graphs and clinical pictures accompany many of the discussions. A unique initial summary page facilitates the reading of each presentation. Recent relevant genetic and biochemical ? ndings in every chapter were particularly helpful to this reader.

Malignant Cutaneous Neoplasms.- Angiosarcoma.- Cutaneous B-Cell Lymphoma.- Granulomatous Slack Skin.- Langerhans Cell Histiocytosis.- Leukemia Cutis.- Mast Cell Disease (Urticaria Pigmentosa).- Merkel Cell Carcinoma.- Metastatic Carcinoma.- Paget’s Disease.- Subcutaneous Panniculitis-like Lymphoma.- Hereditary Cancer-Predisposition Syndromes and Paraneoplastic Disorders.- Muir-Torre Syndrome.- Acquired Ichthyosis, Acanthosis Nigricans, Palmar Hyperkeratosis.- Amyloidosis: Systemic, Nodular, and Epidermal Derived.- Birt-Hogg-Dubé Syndrome.- Cowden’s Syndrome.- Gyrate Erythemas: Erythema Gyratum Repens and Erythema Chronicum Migrans.- Gardner Syndrome.- Multicentric Reticulohistiocytosis.- Multiple Cutaneous Leiomyomas.- Lethal Non-Langerhans Cell Histiocytoses: Necrobiotic Xanthogranuloma and Xanthoma Disseminatum.- Pancreatic Panniculitis.- Scleromyxedema.- Necrolytic Migratory Erythema.- Infectious Diseases.- Anthrax.- Ecthyma Gangrenosum.- Rocky Mountain Spotted Fever and the Rickettsioses.- Smallpox.- Staphylococcal Toxin-Mediated Scalded Skin and Toxic Shock Syndromes.- Meningococcemia and Purpura Fulminans.- Inborn Errors of Metabolism and Autoimmune Disease.- Lethal Hereditary Vascular Disorders: Osler-Weber-Rendu, Ataxia-Telangiectasia, and Fabry’s Disease.- Eruptive Xanthoma.- Graft-versus-Host Disease.- Paraneoplastic Pemphigus and Pemphigus Vulgaris.- Relapsing Polychondritis.- Vascular Diseases.- Calciphylaxis (Calcific Uremic Arteriolopathy).- Kawasaki Disease.- Polyarteritis Nodosa.

Almost exactly ten years ago, two young physicians joined me at the University of Oklahoma for the study of dermatopathology: Stephen C. Somach, a brilliant dermatologist-scholar from Cleveland, who was also a highly accomplished cellist, and Michael B. Morgan, an effervescent, newly minted pathologist from Florida, who was brimming with energy, curiosity, and zeal and was also spo- ing water skiis and a red Porsche! Bruce R. Smoller, whose impressive erudition is universally acknowledged, I met during a Residency Review committee visit to Stanford some ?fteen years ago. Each of these men has made original cont- butions to the dermatopathology literature as well as to patient care in the cli- cal setting. Their publications have broadened our understanding of the biologic behavior of pigmented lesions, cutaneous lymphomas, vascular lesions, and soft tissue tumors. It is indeed a pleasure to welcome their volume, Deadly Der- tologic Diseases, a unique and stimulating outcome of their enthusiastic collaboration. Deadly Dermatologic Diseases discusses a wide variety of entities–neoplastic, vascular, infectious, metabolic–each of which may eventuate in death of the patient. In addition, numerous tumors and dermatoses frequently associated with internal malignancies are reviewed. High-quality histologic photomic- graphs and clinical pictures accompany many of the discussions. A unique initial summary page facilitates the reading of each presentation. Recent relevant genetic and biochemical ? ndings in every chapter were particularly helpful to this reader.