Transplantation at a Glance

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Menna Clatworthy is at the University of Cambridge and Addenbrooke's Hospital
 
Christopher Watson is at the School of Clinical Medicine, University of Cambridge
 
Michael Allison is at Cambridge University Hospitals NHS Foundation Trust
 
John Dark is Professor of Cardiothoracic Surgery at the Regional Cardiothoracic Centre, The Freeman Hospital, Newcastle upon Tyne
Preface 7
 
List of abbreviations 8
 
1 History of transplantation 10
 
Organ donors
 
2 Diagnosis of death and its physiology 12
 
3 Deceased organ donation 14
 
4 Live donor kidney transplantation 16
 
5 Live donor liver transplantation 18
 
Organ preservation
 
6 Organ preservation 20
 
Immunology of organ transplantation
 
7 Innate immunity 22
 
8 Adaptive immunity and antigen presentation 24
 
9 Humoral and cellular immunity 26
 
Histocompatibility in transplantation
 
10 Tissue typing and HLA matching 28
 
11 Detecting HLA antibodies 30
 
12 Antibody-incompatible transplantation 32
 
Organ allocation
 
13 Organ allocation 34
 
Immunosuppression
 
14 Immunosuppression: induction vs maintenance 36
 
15 Biological agents 37
 
16 T cell-targeted immunosuppression 38
 
Complications of immunosuppression
 
17 Side effects of immunosuppressive agents 40
 
18 Post-transplant infection 42
 
19 CMV infection 44
 
20 Post-transplant malignancy 46
 
Kidney transplantation
 
21 End-stage renal failure 48
 
22 Complications of ESRF 50
 
23 Dialysis and its complications 52
 
24 Assessment for kidney transplantion 54
 
25 Kidney transplantation: the operation 56
 
26 Surgical complications of kidney transplantation 58
 
27 Delayed graft function 60
 
28 Transplant rejection 62
 
29 Chronic renal allograft dysfunction 64
 
Pancreas and islet transplantation
 
30 Transplantation for diabetes mellitus 66
 
31 Pancreas transplantation 68
 
32 Islet transplantation 70
 
Liver transplantation
 
33 Causes of liver failure 72
 
34 Assessment for liver transplantation 74
 
35 Liver transplantation: the operation 76
 
36 Complications of liver transplantation 78
 
Intestinal transplantation
 
37 Intestinal failure and assessment 80
 
38 Intestinal transplantation 82
 
Heart transplantation
 
39 Assessment for heart transplantation 84
 
40 Heart transplantation: the operation 86
 
41 Complications of heart transplantation 88
 
Lung transplantation
 
42 Assessment for lung transplantation 90
 
43 Lung transplantation: the operation 92
 
44 Complications of lung transplantation 94
 
Composite tissue transplantation
 
45 Composite tissue transplantation 96
 
Xenotransplantation
 
46 Xenotransplantation 98
 
Index 100
The first basic overview of all aspects of transplantation with a clarity not to be found in more inaccessible textbooks.
 
This brand new title provides a succinct overview of both the scientific and clinical principles of organ transplantation and the types of organ transplant, featuring highly-illustrated information covering core topics in transplantation including:
* Organ donors
* Organ preservation
* Assessment of transplant recipients
* Indications for transplantation
* Immunology of transplantation
* Immunosuppression and its complications
* Overviews of thoracic and abdominal organ transplantation, including the kidneys, liver, heart and lungs
 
Transplantation at a Glance is the ideal introduction for medical students, junior doctors, surgical trainees, immunology students, pharmacists, and nurses on transplant wards.

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