This second editionis a ground-breaking clinical text with a strong emphasis on rigorous evidence. Leaders in the field discuss best practice in the light of systematic reviews and randomised control trials, and how best to treat where the information is less clear. Case histories provide intriguing discussions on how to apply the evidence in real life situations. Evidence-based Cardiology also includes free access to the latest evidence, which is automatically posted on a companion website.

This second editionis a ground-breaking clinical text with a strongemphasis on rigorous evidence. Leaders in the field discuss bestpractice in the light of systematic reviews and randomised controltrials, and how best to treat where the information is less clear.Case histories provide intriguing discussions on how to apply theevidence in real life situations.Evidence-based Cardiology also includes free access tothe latest evidence, which is automatically posted on a companionwebsite.

Approaches to evaluating evidence.A critical appraisal of the cardiovascular history and physical examination.Obtaining incremental information from diagnosis tests.Finding current best evidence to practice evidence based cardiology.Understanding concepts related to health economics.Introduction to decision analysis.Assessing and changing cardiovascular clinical practices.Learning from clinical practice.Global perspective on cardiovascular disease.Tobacco: global burden and community solutions.Tobacco and cardiovascular disease.Use of lipid lowering agents in the prevention of cardiovascular disease.Use of lipid lowering agents in the prevention of cardiovascular disease.Blood pressure and cardiovascular disease.Glucose abnormalities and cardiovascular disease: dysglycemia as an emerging cardiovascular risk fac.Physical activity and exercise in cardiovascular disease prevention and rehabilitation.Psychosocial factors in the primary and secondary prevention of coronary heart disease: a sys review.Emerging approaches in cardiovascular prevention.Cost-effectiveness of prevention of cardiovascular disease.Estrogens and cardiovascular disease.Ethnicity and cardiovasculr disease.Anti-ischemic drugs.Chronic coronary artery disease: coronary artery bypass surgery vs percutaneous transluminal.coronary angioplasty vs medical therapy.Unstable angina.Thrombolytic therapy.Mechanical reperfusion strategies in patients presenting with acute myocardial infarction.Adjunctive antithrombotic therapy for acute myocardial infarction.Pain relief, general management and other adjunctive treatments.Complications after myocardial infarction.An integrated approach to the management of patients after the acute phase of myocardial infarction.Atrial fibrillation: anti-arrhythmic therapy.Atrial fibrillation: antithrombotic therapy.Strial fibrillation: non-pharmacologic therapies.Supraventricular thachycardia: drugs vs ablation.Therapy for primary prevention of life threatening ventricular arrythmias.Impact of pace-makers: when and what kind.Syncope.Management of overt heart failure.Acute myocarditis and dilated cardiomyopathy.Prevention of congestive heart failure and treatment of asymptomatic left ventricular dysfunction.Hypertrophic cardiomyopathy.Other cardiomyopathies.Pericardial disease: an evidence-based approach to diagnosis and treatment.Rheumatic heart disease: prevention and acute treatment.Mitral valve disease.Indications for surgery in aortic valve disease.Balloon valvuloplasty: aortic valve.Balloon valvuloplasty: mitral valve.Valve repair and choice of valves.Diagnosis and management of infective endocarditis.Antithrombotic therapy after heart valve replacement.Pregnancy in heart disease.Coronary intervention: angioplasty, stents and atherectomy.Adjunctive therapy in PTCA.Restenosis: etiologies and prevention.The prevention of ischemic stroke.Venous thromboembolic disease.Peripheral vascular disease.Stable angina: choice of PTCA vs CABG vs drugs.Unstable angina: management issues.Postmyocardial infarction: routine prophylaxis.Postmyocardial infarction risk factor modification: dyslipoproteinemias.Peripheral vasculae disease with suspect coronary artery disease: management issues.Congestive heart failure.Atrial fibrillation: management issues.Ventricular dysrhythmias: pharmacology vs non-pharmacology treatment.Bradyarrythmias: choice of pacemaker.Valvular heart disease: timing of surgery.Clinical trials and meta analysis.Fetal origins of cardiovascular disease.Genetics.Obesity.CPR chapter.Introduction to clinical applications