Physics of Cancer: Second edition, volume 2
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Physics of Cancer: Second edition, volume 2

Cellular and microenvironmental effects
 EPUB
Sofort lieferbar | Lieferzeit:3-5 Tage I
ISBN-13:
9780750321174
Einband:
EPUB
Seiten:
431
Autor:
Claudia Mierke
Serie:
IOP Expanding Physics
eBook Typ:
Adobe Digital Editions
eBook Format:
EPUB
Kopierschutz:
Adobe DRM [Hard-DRM]
Sprache:
Englisch
Beschreibung:

This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.

In order to increase the healing opportunities of cancer, it is important to impair the dissemination and the spreading of cancer cells from the initial tumor and the formation of metastases in other organs or tissues of the human body. The underlying physical principles of these oncological processes are a major constituent of the research field highlighted in Physics of Cancer.



This completely revised second edition of is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.

Preface


About the author


Introduction


1 Initiation of a neoplasm or tumor                                                                          


2 Inflammation and cancer                                                                                        


3 Cellular stiffness and deformability                                              


4 Cell–cell and cell–matrix adhesion strength, local cell stiffness and forces


5 Cell surface tension, the mobility of cell surface receptors and their location in specific regions


6 Cytoskeletal remodeling dynamics                                                            


7 Actin filamen during matrix invasion


8 Intermediate filaments during matrix invasion                                                   


9 Microtubules during migration and matrix invasion                             


10 Nuclear deformability during migration and matrix invasion


11 The mechanical and structural properties of the microenvironment


12 The impact of cells and substances within the extracellular matrix tissue on mechanical properties and cell invasion


13 The active role of the tumor stroma in regulating cell invasion


14 The role of endothelial cell-cell adhesions                                                        


15 The mechanical properties of endothelial cells altered by aggressive cancer cells


16 The role of macrophages during cancer cell transendothelial migration

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