Written by experts in the field, this important book provides anintroduction to current risk assessment practices and proceduresand explores the intrinsic complexities, challenges, andcontroversies associated with analysis of environmental healthrisks.Environmental Health Risk Assessment for Public Healthoffers 27 substantial chapters on risk-related topics thatinclude:* What Is Risk and Why Study Risk Assessment* The Risk Assessment-Risk Management Paradigm* Risk Assessment and Regulatory Decision-Making in EnvironmentalHealth* Toxicological Basis of Risk Assessment* The Application of PBPK Modeling to Risk Assessment* Probabilistic Models to Characterize Aggregate and CumulativeRisk* Molecular Basis of Risk Assessment* Comparative Risk Assessment* Occupational Risk* Radiological Risk Assessment* Microbial Risk Assessment* Children's Risk Assessment* Life Cycle Risk* Environmental Laws and Regulations* Precautionary Principles* Risk Communication

Figures, Tables, and Exhibits xiPreface xviiAbout the Editors xxiAbout the Contributors xxiii1 Introduction to Risk Assessment in Public Health 1Mark Robson and Fred Ellerbusch2 The Risk Assessment-Risk Management Paradigm 11Gilbert S. Omenn3 Risk Assessment and Regulatory Decision Making inEnvironmental Health 31Felicia Wu and William H. Farland4 Toxicological Basis for Risk Assessment 55Tee L. Guidotti and Marina S. Moses5 The Application of Physiologically Based Pharmacokinetic(PBPK) Modeling to Risk Assessment 85Raymond S. H. Yang and Yasong Lu6 Probabilistic Models for Characterizing Aggregate andCumulative Risk 121John L. Adgate and Gurumurthy Ramachandran7 Molecular Tools for Risk Assessment 155William A. Toscano and Chisato Mori8 Comparative Risk Assessment 173Michele Morrone9 Risk in the Workplace: Where Analysis Began and ProblemsRemain Unsolved 187Adam M. Finkel and P. Barry Ryan10 Radiological Risk Assessment 239Ronald O. Rahn and Arthur C. Upton11 Microbial Risk Assessment 285Rebecca T. Parkin12 Children's Risk Assessment 315Natalie C. G. Freeman13 Biological Monitoring of Exposure to Environmental ChemicalsThroughout the Life Stages: Requirements and Issues to Consider forBirth Cohort Studies 345Dana B. Barr, Richard Y. Wang, and Larry L. Needham14 Overview of Environmental Public Health Laws and TheirRelation to Risk 383Russellyn S. Carruth and Bernard D. Goldstein15 Why Risk Assessment Is Not Enough to Protect Health:Rationale for a Precautionary Approach to Science and Policy423Joel A. Tickner16 Risk Communication 463Susan L. SantosCASE STUDIES IN RISK ASSESSMENT17 Improvement of Risk Assessments for Multicontaminant Sites inthe Face of Critical Data Gaps 489Yoram Cohen and Adrienne Katner18 Intraspecies Differences in Acute Acrylonitrile Toxicity511Gwendolyn Ball, Clif McLellan, and Lori Bestervelt19 Drinking Water Contamination by Perchlorates from Departmentof Defense Rocket Fuel Facilities 517Terry Gratton and Norman Trieff20 Multi-Pathway Risk Assessment for Children Living Near aHazardous Waste Site 523Serap Erdal21 Child with Asthma Living in a Moisture-Damaged Home 531Myrtis Sullivan22 Endocrine Disruption Through Phthalates/Plasticizers541Christine Ziebold23 Estimation of Health and Safety Risks from Exposure toChlorine and Chloroform for Swimmers in Pools 547Richard P. Hubner24 U-Shaped Dose-Response Curve for Risk Assessment of EssentialTrace Elements: Copper as a Case Study 555Bonnie Ransom Stern25 Ecosystem Risk Assessment: The Neuse River Estuary, NorthCarolina 563Craig A. Stow, Mark E. Borsuk, and Kenneth H. Reckhow26 The Ohio Comparative Risk Project 587Michele Morrone27 Community-Based Risk Assessment: DDT Contamination in Triana,Alabama 597Padma Tadi-UppalaName Index 605Subject Index 611