Handbook of Platelet Physiology and Pharmacology

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Contributors. Preface. Introduction. 1. Platelet Physiology & Pharmacology: An overview; G.H.R. Rao. Receptor Biology. 2. Human Platelet Thrombin Receptors and the two Receptor Model for Platelet Activation; G.A. Jamieson, et al. 3. Platelet Thromboxane Receptors: Biology and Function; G.J. Johnson. 4. Collagen Receptors: Biology and Functions; B. Kehrel. 5. Adenosine Receptors: Biology and Function; K.C. Agarwal. 6. Platelet Activating Factor and Platelets; S.D. Shukla. 7. Platelet Glycoprotein 1b-V-1X: Biology and Function; K.J. Clemetson. 8. Fibrinogen Receptors: Biology and Function; E.I. Peerschke. Platelet Biochemistry. 9. Biochemistry of Platelet Activation; A. Ryningen, H. Holmsen. 10. GTP Binding Proteins in Platelets; B.R. Lester. 11. Platelet Cyclic Nucleotide Phosphodiesterases; R.W. Colman. 12. Polyenoic Fatty Acids and Platelet Function; M. Murthy. 13. Phospholipase A2 in Platelets; M. Murthy. Experimental Physiology. 14. Platelet Biorheology: Adhesive Interactions in Flow; M.M. Frojmovic. 15. Platelet Vessel Wall Interactions; G. Escolar, M. Diaz-Ricart. 16. Platelet-Biomaterial Interactions; T. Chandy and G.H.R. Rao. 17. Comparative Physiology of Platelets from Different Species; D.J. Weiss. Platelet Pathology. 18. The Molecular Pathology of Glanzmann's Thrombasthenia; D. French. 19. Congenital Disorders of Platelet Signal Transduction and Secretion; A. Koneti Rao. 20. Biochemistry of Altered Platelet Reactivity in Hypertension; Huzoor-Akbar. Platelet Pharmacology. 21. Nitric Oxide-mediated Regulation of Platelet Function; M.W. Radomski, A.S. Rodomski. 22. Aspirin, Prostaglandins and Platelet Function: Pharmacology and Thrombosis Prevention; D.C. Calverley, G.J. Roth. 23. Current Developments in Anticoagulant and Antithrombotic Agents; J. Fareed, et al. 24. Randomized Trials of Antiplatelet Therapy; C. Sudlow, C. Baigent. Subject Index.

This is the first comprehensive work to review blood platelet biochemistry, physiology, pharmacology, and function. It provides up-to-date information on how platelets function, the biochemical mechanisms that modulate their physiology and function, as well as the pharmacology of platelet inhibitory drugs.

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