List of contributors; Part I. Prepregnancy Problems: 1. Constitutional and environmental factors leading to a high risk pregnancy; 2. Domestic violence in pregnancy; 3. Female genital mutilation and pregnancy; 4. Genetics, risks of recurrence, and genetic counselling; Part II. Early Prenatal Problems: 5. Bleeding and pain in early pregnancy; 6. Recurrent miscarriage; 7. Screening for fetal abnormality in the first and second trimesters; 8. Invasive procedures for prenatal diagnosis; Part III. Late Prenatal - Fetal Problems: 9. Prenatal fetal surveillance; 10. Fetal growth disorders; 11. Disorders of amniotic fluid; 12. Fetal Hemolytic disease; 13. Fetal thrombocytopenia; 14. Fetal cardiac arrhythmias; 15. Fetal cardiac abnormalities; 16. Fetal craniospinal and facial abnormalities; 17. Fetal genitourinary abnormalities; 18. Fetal gastrointestinal abnormalities; 19. Fetal skeletal abnormalities; 20. Fetal tumors; 21. Fetal Hydrops; 22. Fetal death; Part IV. Problems Associated with Infection: 23. Intrauterine infection, preterm parturition, and the fetal inflammatory response syndrome; 24. Hepatitis viruses in pregnancy; 25. Human immunodeficiency virus in pregnancy; 26. Rubella, measles, mumps, varicella, and parvovirus in pregnancy; 27. Cytomegalovirus, herpes simplex virus, adenovirus, coxsackievirus, and human papillomavirus in pregnancy; 28. Parasitic infections in pregnancy; 29. Other infectious conditions in pregnancy; Part V. Late Pregnancy - Maternal Problems: 30. Substance misuse in pregnancy; 31. Medication in pregnancy; 32. Hypertension in pregnancy; 33. Cardiac disease in pregnancy; 34. Respiratory disease in pregnancy; 35. Anemia and white blood cell disorders in pregnancy; 36. Haematological malignancies in pregnancy; 37. Thrombocytopenia and bleeding disorders in pregnancy; 38. Disorders of coagulation in pregnancy; 39. Autoimmune disease in pregnancy; 40. Diabetes in pregnancy; 41. Thyroid disease in pregnancy; 42. Pituitary and adrenal disease in pregnancy; 43. Gastrointestinal and liver diseases in pregnancy; 44. Neurologic disorders in pregnancy; 45. Renal disorders in pregnancy; 46. Spine and joint disorders in pregnancy; 47. Skin disease in pregnancy; 48. Malignant disease in pregnancy; 49. Pregnancy after transplantation; 50. Trauma in pregnancy; 51. Mental health disorders in pregnancy; Part VI. Late Prenatal - Obstetric Problems: 52. Abdominal pain in pregnancy; 53. Nonmalignant gynecology in pregnancy; 54. Bleeding in late pregnancy; 55. Multiple pregnancy; 56. Threatened and actual preterm labour, including screening and mode of delivery; 57. Prelabor rupture of the membranes; 58. Breech presentation, unstable lie, malpresentation, and malpositions; 59. Prolonged pregnancy; 60. Induction of labor and termination of the previable pregnancy; 61. Dysfunctional labour; 62. Shoulder dystocia; 63. Fetal compromise in labour; 64. Neuraxial Analgesia and Anesthesia in obstetrics; 65. Perineal repair and pelvic floor injury; 66. Assisted vaginal delivery; 67. Delivery after previous caesarean section; 68. Caesarean section; Part VII. Postnatal Problems: 69. Postpartum hemorrhage and other problems of the third stage; 70. Puerperal problems; 71. Major obstetric haemorrhage (MOH) and disseminated intravascular coagulation (DIC); 72. Critical care in obstetrics; 73. Resuscitation and immediate care of the newborn; Part VIII. Normal Values: 74. Normal values in pregnancy.

Answers key questions for clinicians caring for a high-risk pregnancy. Online content will be reviewed annually and updated as needed.