The first practical guide for hospitalists on the use ofanticoagulants in hospitalized patientsThis edited volume provides a comprehensive overview of thevital topic of anticoagulation in the hospital setting. Designedspecifically for use by hospital-based clinicians and associatedhospital-based staff, this fully evidence-based book addresses themost commonly used anticoagulant agents, the latest advances inanticoagulation drugs, and primary indications for their use attherapeutic levels.This thorough, easy-to-use reference summarizes the mostimportant guidelines and medical literature on anticoagulation. Itfeatures a careful review of the epidemiology and treatment ofcomplications associated with anticoagulants. Unique topics includetransition of care and practical strategies for developing andimplementing quality improvement programs to enhance theadministration and safety of anticoagulants.This concise resource also covers:* Antiplatelet medications* The treatment and prevention of venous thromboembolism inmedical patients* Venous thromboembolism prophylaxis in surgical patients* Peri-operative management of oral anticoagulants andantiplatelet agents* Prevention of cardioembolic stroke* Antithrombotics for ischemic stroke* Antithrombotic therapy for non-ST elevation acute coronarysyndrome* Hemorrhagic complications of anticoagulants in hospitalizedpatients* Heparin-induced thrombocytopeniaHospitalists and other members of the patient care team willfind that Inpatient Anticoagulation answers their questions withdependable and timely information.

Preface viiContributors ix1. Pharmacology of Parenteral Anticoagulants 1Kathleen H. McCool and Daniel M. Witt2. Pharmacology of Vitamin K Antagonists 25Jaekyu Shin and Steven R. Kayser3. Antiplatelet Medications 47Michael Kornfeld and Joseph R. Munsayac4. Newer Oral Anticoagulants 67Taki Galanis and Geno J. Merli5. Prevention of Venous Thromboembolism in Medical Patients81Alex C. Spyropoulos and Charles E. Mahan6. Prevention of Venous Thromboembolism in Surgical Patients107Nancy Torres Finnerty and Franklin Michota7. Treatment of Acute Venous Thromboembolism in HospitalizedPatients 137Tracy Minichiello, Lauren Doctoroff, and Elizabeth A.Farrell8. Perioperative Management of Oral Anticoagulants andAntiplatelet Agents 161Ramiro Jervis and Andrew Dunn9. Prevention of Cardioembolic Stroke 179Ali Mahajerin and Warren J. Manning10. Antithrombotics for Ischemic Stroke 205Fadi B. Nahab and Sakib Qureshi11. Antithrombotic Therapy for Non-ST-Elevation AcuteCoronary Syndrome 223David Lao and Andrew Boyle12. Parenteral Anticoagulants: Special Considerations inPatients with Chronic Kidney Disease and Obesity 241Sarah A. Spinler, Millie Rajyaguru, Julie K. Atay, and JohnFanikos13. Hemorrhagic Complications of Anticoagulants inHospitalized Patients 291Allison Burnett, Jason Cohen, and David A. Garcia14. Heparin-Induced Thrombocytopenia 331David Feinbloom and John Fani Srour15. Transitions in Care: Inpatient Anticoagulation 361Neil Gupta, Diane Sliwka, and Margaret C. Fang16. Optimizing Inpatient Anticoagulation: Strategies forQuality Improvement 377Greg Maynard, Ian Jenkins, Brian Clay, Michael Montazeri,and Doug HumberIndex 415