Derek Raghavan, MD, PhD, is President of the Levine Cancer Institute of the Carolinas Healthcare System in Charlotte, North Carolina. Widely published in journals and books, Dr. Raghavan has been the editor-in-chief of Textbook of Uncommon Cancer since its second edition.
Charles D. Blanke, MD, is Chief of the Division of Oncology at the British Columbia Cancer Agency and Professor of Medicine at the University of British Columbia in Vancouver, Canada.

David Johnson, MD, was the longtime Director of the Division of Hematology and Oncology at Vanderbilt University in Nashville, Tennessee, and was recently appointed as Chairman of Medicine and holds the Donald W. Seldin Distinguished Chair in Internal Medicine at the University of Texas Southwestern in Dallas, Texas.

Paul L. Moots, M.D., Associate Professor of Neurology at the Vanderbilt-Ingram Cancer Center in Nashville, Tennessee.

Gregory H. Reaman, M.D., is Chair of the Children's Oncology Group at the Children's National Medical Center in Washington, DC.

Peter G. Rose, MD, is Section Head and Fellowship Director of Gynecologic Oncology in the Department of Obstetrics and Gynecology at the Cleveland Clinic.

Mikkael A. Sekeres, MD, is Director of the Leukemia Program at the Cleveland Clinic Taussig Cancer Institute.

List of Contributors, ix

Preface, xvii

List of Abbreviations, xix

Section 1 Genitourinary Cancer

1 Uncommon Tumors of the Kidney, 1
Khaled Ali, Ming Zhou, Steve Campbell, Ronald M. Bukowski, and Brian I. Rini

2 Uncommon Cancers of the Bladder, 23
Arlene O. Siefker-Radtke, Bogdan A. Czerniak, Colin P. Dinney, and Randall E. Millikan

3 Urethral Cancer, 35
Sonia L. Ali, Tanya B. Dorf, Paul G. Pagnini, and David I. Quinn

4 Uncommon Cancers of the Prostate, 47
Scott T. Tagawa, Naveed H. Akhtar, Brian D. Robinson, and Himisha Beltran

5 Rare Tumors of the Testis and Paratesticular Tissues, 77
Robert Huddart, Stephen Hazell, and Alan Horwich

Section 2 Head and Neck Cancer

6 Uncommon Tumors of the Oral Cavity and Adjacent Structures, 97
Voichita Bar-Ad, Madalina Tuluc, David Cognetti, and Rita Axelrod

7 Rare Tumors of the Larynx, 119
Kyle Mannion, Kenneth J. Niermann, Joseph M. Aulino, and Barbara A. Murphy

8 Nasopharyngeal Carcinoma in Nonendemic Populations, 131
June Corry and Bonnie S. Glisson

9 Esthesioneuroblastoma, 151
Barbara A. Murphy, Salyka Sengsayadeth, Joseph M. Aulino, Christine H. Chung, Kim Ely, Robert J. Sinard, and Anthony J. Cmelak

Section 3 Endocrine Tumors

10 Adrenal Neoplasms, 163
Alexandria T. Phan, Mouhammed A. Habbra, Elizabeth G. Grubbs, and Cesar Moran

11 Uncommon Cancers of the Thyroid, 189
Sonia Abuzakhm, Mark Bloomston, and Manisha H. Shah

12 Parathyroid Carcinoma, 201
Rodrigo Arrangoiz and John A. Ridge

Section 4 Breast Cancer

13 Metaplastic Breast Carcinoma, 211
Ingrid A. Mayer, Helenice Gobbi, and A. Bapsi Chakravarthy

14 Adenoid Cystic Carcinoma of the Breast, 217
Melinda E. Sanders, Masako Kasami,

Julie Means-Powell, and David L. Page

15 Non-Hodgkin Lymphoma of the Breast, 225
David S. Morgan and Jean F. Simpson

16 Male Breast Cancer, 233
Nicole M. Randall, Kathy D. Miller, and George W. Sledge Jr.

17 Phyllodes Tumor of the Breast, 243
Emad A. Rakha and Ian O. Ellis

18 Carcinosarcoma of the Breast, 257

Stacy L. Moulder, Bryan T. Hennessy, Michael Z. Gilcrease, Gildy Babiera, Wei Yang, Vicente Valero, and Gabriel N. Hortobagyi

19 Tubular Carcinoma, 271
Melinda E. Sanders, Ingrid A. Mayer, and A. Bapsi Chakravarthy

Section 5 Thoracic Tumors

20 Thymoma and Thymic Carcinoma, 279
Patrick J. Loehrer Sr., Mark R. Wick, and Sunil Badve

21 Primary Sarcomas of the Lung, 303
Regan M. Duffy, Amanda VanSandt, and Alan B. Sandler

22 Mesotheliomas, 319
Giuseppe Giaccone, Anish Thomas, and Arun Rajan

23 Primary Melanoma of the Lung, 335
Richard A. Scolyer, James F. Bishop, and John F. Thompson

24 Large Cell Neuroendocrine Carcinoma, 343
William D. Travis, M. Catherine Pietanza, and Inderpal (Netu) S. Sarkaria

25 Bronchioloalveolar Carcinoma of the Lung, 355
Gregory J. Riely and Vincent A. Miller

26 Primary Adenoid Cystic Carcinoma of the Lung, 365
John G. Devlin and Corey J. Langer

Section 6 Gastrointestinal Tumors

27 Uncommon Tumors of the Esophagus, 373
Lawrence Leichman and Robert Rosser

28 Uncommon Cancers of the Stomach, 389
Elizabeta Popa, Felice Schnoll-Sussman, Arun Jesudian, Govind Nandakumar, and Manish A. Shah

29 Unusual Cancers of the Pancreas, 409
Chanjuan Shi, John S. Macdonald, and Jordan D. Berlin

30 Uncommon Hepatobiliary Tumors, 423
Abby B. Siegel, Vladimir Sheynzon, and Benjamin Samstein

31 Cancers of the Small Bowel, 441
Kanwal Raghav, Matthew H. G. Katz, and Michael J. Overman

32 Unusual Tumors of the Colon, Rectum, and Anus, 453
Diane Reidy-Lagunes, Karyn Goodman, and Leonard B. Saltz

33 Gastrointestinal Stromal Tumors, 465
Margaret von Mehren, Douglas B. Flieder, and Chandrajit P. Raut

Section 7 Gynecological Cancers

34 Extraovarian Primary Peritoneal Carcinomas, 485
Alberto E. Selman and Larry J. Copeland

35 Borderline Tumors and Other Rare Epithelial

Tumors of the Ovary, 497
Ramez N. Eskander, Teresa P. Díaz-Montes, Russ

The only text dealing exclusively with rare or infrequently encountered malignancies in adults and children

Now in its Fourth Edition, Textbook of Uncommon Cancer is designed to help clinicians manage the treatment of uncommon cancers, for which, in many instances, there are few established guidelines for care. No longer does each new presentation of an uncommon cancer require extended periods of research. This unique and well-established book provides balanced, authoritative, and now, wherever possible, evidence-based guidance on how to address each malignancy.

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Features of this new edition include:
A complete revision and update, with five new chapters and extensive revisions of more than 75 percent of the existing chapters
Over 100 new full-color illustrations and images
Contributions by multidisciplinary teams of medical oncologists, radiation oncologists, and other specialists, reflecting day-to-day decision-making and clinical practice

Textbook of Uncommon Cancer, Fourth Edition is an essential, self-contained guide for practicing oncologists who treat patients with rare or infrequently encountered malignancies. It is also an important resource for hematologists and other specialists who deal with malignancies in a particular organ system.