The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing together the work of experts in academia and industry, Protein and Peptide Mass Spectrometry in Drug Discovery highlights current analytical approaches, industry practices, and modern strategies for the characterization of both peptides and proteins in drug discovery. Illustrating the critical role MS technology plays in characterizing target proteins and protein products, the methods used, ion mobility, and the use of microwave radiation to speed proteolysis, the book also covers important emerging applications for neuroproteomics and antigenic peptides. Placing an emphasis on the pharmaceutical industry, the book stresses practice and applications, presenting real-world examples covering the most recent advances in mass spectrometry, and providing an invaluable resource for pharmaceutical scientists in industry and academia, analytical and bioanalytical chemists, and researchers in protein science and proteomics.

The book that highlights mass spectrometry and its applicationin characterizing proteins and peptides in drug discoveryAn instrumental analytical method for quantifying the mass andcharacterization of various samples from small molecules to largeproteins, mass spectrometry (MS) has become one of the most widelyused techniques for studying proteins and peptides over the lastdecade. Bringing together the work of experts in academia andindustry, Protein and Peptide Mass Spectrometry in DrugDiscovery highlights current analytical approaches, industrypractices, and modern strategies for the characterization of bothpeptides and proteins in drug discovery.Illustrating the critical role MS technology plays incharacterizing target proteins and protein products, the methodsused, ion mobility, and the use of microwave radiation to speedproteolysis, the book also covers important emerging applicationsfor neuroproteomics and antigenic peptides. Placing an emphasis onthe pharmaceutical industry, the book stresses practice andapplications, presenting real-world examples covering the mostrecent advances in mass spectrometry, and providing an invaluableresource for pharmaceutical scientists in industry and academiaanalytical and bioanalytical chemists, and researchers in proteinscience and proteomics.