Neurophysiology of Neuroendocrine Neurons provides researchers and students with not only an understanding of neuroendocrine cell electrophysiology, but also an appreciation of how this model system affords access to virtually all parts of the neuron for detailed study - something unique compared to most types of neuron in the brain. Chapters range from those describing the rich history and current state of in vivo recordings, highlighting the precise relationship between the patterns of action potential discharge in these neurons and hormone release, to in vitro approaches where neuroendocrine neurons can be precisely identified and their membrane properties, morphology, and synaptic responses, directly examined. Written by a team of internationally renowned researchers, each chapter presents a succinct summary of the very latest developments in the field Includes an evaluation of different experimental approaches, both in vivo and in vitro, and how the resulting data are interpreted Both print and enhanced e-book versions are available Illustrated in full colour throughout This is the first volume in a new Series Masterclass in Neuroendocrinology , a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Neurophysiology of Neuroendocrine Neurons provides researchersand students with not only an understanding of neuroendocrine cellelectrophysiology, but also an appreciation of how this modelsystem affords access to virtually all parts of the neuron fordetailed study - something unique compared to most types of neuronin the brain. Chapters range from those describing the rich historyand current state of in vivo recordings, highlighting the preciserelationship between the patterns of action potential discharge inthese neurons and hormone release, to in vitro approaches whereneuroendocrine neurons can be precisely identified and theirmembrane properties, morphology, and synaptic responses, directlyexamined.* Written by a team of internationally renownedresearchers, each chapter presents a succinct summary of the verylatest developments in the field* Includes an evaluation of different experimentalapproaches, both in vivo and in vitro, and how the resulting dataare interpreted* Both print and enhanced e-book versions areavailable* Illustrated in full colour throughoutThis is the first volume in a new Series'Masterclass in Neuroendocrinology' , a co- publicationbetween Wiley and the INF (International Neuroendocrine Federation)that aims to illustrate highest standards and encourage the use ofthe latest technologies in basic and clinical research and hopes toprovide inspiration for further exploration into the exciting fieldof neuroendocrinology.

List of Contributors, viiSeries Preface, ixPreface, xiAbout the Companion Website, xiiiSection 1A Magnocellular Neuroendocrine Neurons: Propertiesand Control of Vasopressin and Oxytocin Neurons1 Electrophysiology of Magnocellular Neurons In Vivo, 3Gareth Leng and Nancy Sabatier2 Oxytocin Neurons during Suckling: Lessons from OrganotypicCultures, 29Jean-Marc Israel and Dominique A. Poulain3 Peptidergic Control of Oxytocin and Vasopressin Neurons andIts Role in Reproductive and Hypertension-Associated Plasticity63Colin H. Brown, Su Young Han, Mahsa Moaddab, Victoria Scott, andDaryl O. Schwenke4 The Osmotic Control of Vasopressin-Releasing Neurons, 85Katrina Y. Choe and Charles W. Bourque5 Function and Localization of Epithelial Sodium Channels inVasopressin and Oxytocin Neurons, 105Ryoichi Teruyama6 Visible Markers of Vasopressin and Oxytocin Activity and TheirUse in Identifying the Neuronal Activity of Specific NeuroendocrineCell Types, 135Toyoaki Ohbuchi and Yoichi Ueta7 Neurophysiology of Neurohypophysial Terminals, 163José R. Lemos, Gang Wang, Hector Marrero, and SoniaOrtiz-MirandaSection 1B Magnocellular Neuroendocrine Neurons: SynapticPlasticity and the Autoregulation of Vasopressin and OxytocinRelease8 Neuronal-Glia Remodeling of the Magnocellular System189Stéphane H. R. Oliet9 Dendritic Release of the Neuropeptides Vasopressin andOxytocin, 207Mike Ludwig10 Endocannabinoid Modulation of Synaptic Inputs toMagnocellular Neurons, 225Ion R. Popescu, Shi Di, and Jeffrey G. Tasker11 Role of Central Vasopressin in the Generation of MultimodalHomeostatic Responses, 253Javier E. SternSection 2 Gonadotropin-Releasing Hormone Neurons of theParvocellular Neurosecretory System12 Elucidating the Structure and Function ofGonadotropin-Releasing Hormone (GnRH) Neuron Dendrites, 273Karl J. Iremonger and Allan E. Herbison13 Estradiol and Kisspeptin Modulation of Gonadotropin-ReleasingHormone (GnRH) Neuronal Excitability, 301Oline K. Rønnekleiv, Chunguang Zhang, and Martin J.Kelly14 Multiple-Unit Activity Recording of theGonadotropin-Releasing Hormone Pulse Generator, 323Hiroaki Okamura and Yuji MoriGlossary, 347Index, 361