From Boron Trifluoride to Zinc, the 52 most widely used reagents in organic synthesis are described in this unique desktop reference for every organic chemist. The list of reagents contains classics such as N-Bromosuccinimide (NBS) and Trifluoromethanesulfonic Acid side by side with recently developed ones like Pinacolborane and Tetra-n-propylammonium Perruthenate (TPAP). For each reagent, a concise article provides a brief description of all important reactions for which the reagent is being used, including yields and reaction conditions, an overview of the physical properties of the reagent, its storage conditions, safe handling, laboratory synthesis and purification methods. Advantages and disadvantages of the reagent compared to alternative synthesis methods are also discussed. Reagents have been hand-picked from among the 5000 reagents contained in EROS, the Encyclopedia of Reagents for Organic Synthesis. Every organic chemist should be familiar with these key reagents that can make almost every reaction work.

From Boron Trifluoride to Zinc, the 52 most widely used reagents in organic synthesis are described in this unique desktop reference for every organic chemist. The list of reagents contains classics such as N-Bromosuccinimide (NBS) and Trifluoromethanesulfonic Acid side by side with recently developed ones like Pinacolborane and Tetra-n-propylammonium Perruthenate (TPAP).For each reagent, a concise article provides a brief description of all important reactions for which the reagent is being used, including yields and reaction conditions, an overview of the physical properties of the reagent, its storage conditions, safe handling, laboratory synthesis and purification methods. Advantages and disadvantages of the reagent compared to alternative synthesis methods are also discussed.Reagents have been hand-picked from among the 5000 reagents contained in EROS, the Encyclopedia of Reagents for Organic Synthesis. Every organic chemist should be familiar with these key reagents that can make almost every reaction work.

Preface ixShort Note on InChIs and InChIKeys xiGeneral Abbreviations xiiiBis(dibenzylideneacetone)palladium(0) 29-Borabicyclo[3.3.1]nonane Dimer 17Boron Trifluoride Etherate 27N-Bromosuccinimide 43n-Butyllithium 54N,N[1]-Carbonyl Diimidazole 72Cerium(IV) Ammonium Nitrate 80m-Chloroperbenzoic Acid 87N-Chlorosuccinimide 98Chlorotrimethylsilane 108Chlorotris(triphenylphosphine)-rhodium(I) 121(Diacetoxyiodo)benzene 136Diazomethane 1452,3-Dichloro-5,6-dicyano-1,4-benzoquinone 152Diisobutylaluminum Hydride 1644-Dimethylaminopyridine 170Dimethyldioxirane 1761-Ethyl-3-(3[1]-dimethylaminopropyl) carbodiimide Hydrochloride 184N-Iodosuccinimide 188Iodotrimethylsilane 1942-Iodoxybenzoic Acid 206Lithium Aluminum Hydride 212Lithium Diisopropylamide 224Lithium Naphthalenide 241Manganese Dioxide 248Osmium Tetroxide 264Oxalyl Chloride 283Oxalyl Chloride-Dimethylformamide 288Ozone 290Pinacolborane 306Potassium Hexamethyldisilazide 313Potassium Monoperoxysulfate 334Potassium tert-Butoxide 353Ruthenium(II), Tris(2,2[1]-bipyridine-kappaN1,kappaN1[1])-, (OC-6-11)- 370Samarium(II) Iodide 378Scandium Trifluoromethanesulfonate 388Sodium Azide 398Sodium Borohydride 406Sodium Cyanoborohydride 419Sodium Hexamethyldisilazide 428Sodium Hydride 438Sodium Periodate 447Tetrabutylammonium Fluoride 458Tetrakis(triphenylphosphine)-palladium(0) 467Tetra-n-propylammonium Perruthenate 476p-Toluenesulfonyl Chloride 480Triethylsilane 489Trifluoromethanesulfonic Acid 498Trifluoromethanesulfonic Anhydride 507Trimethylsilyl Trifluoromethanesulfonate 524Trimethylsilyldiazomethane 543Zinc-Acetic Acid 554List of Contributors 000Subject Index 000