Hugo & Russell s Pharmaceutical Microbiology Discover the very latest developments in pharmaceutical microbiology in the 9th edition of this popular textbook Microbiology is one of the essential pharmaceutical sciences upon which the study and practice of pharmacy is built. It has a bearing on all aspects of the manufacture of medicines and sterile products, from their design and development to their delivery as quality products. Few interventions are more central to modern medicine than the treatment of infection, where antibiosis, vaccination and hygienic practices have essential roles to play. The COVID-19 pandemic, the appearance of new pathogens and the rise of antibiotic resistance have demonstrated most completely the need for pharmaceutical practitioners, researchers and industrial scientists to be fully conversant with this field. The 9th edition of Hugo and Russell s Pharmaceutical Microbiology has been updated to meet this need. Having long served as the sole comprehensive textbook covering this subject, it has now been adapted to a critical new period in the advancement of medical and pharmaceutical research and development. Its experienced editors have incorporated contributions from subject experts and created a text which will serve the next generation of pharmacy students, pharmaceutical industry scientists and researchers. In this ninth edition of Hugo and Russell s Pharmaceutical Microbiology, readers will find: A mix of established and new authors bringing practical and research experience to their chapters Material covering the fundamentals of microbiology, microbial behavior and laboratory investigation Revised chapters incorporating new material on microbe-host interactions, antibiotic resistance, emerging pathogens, public health microbiology, healthcare-associated infection and pharmaceutical manufacture Emerging understandings from the COVID-19 pandemic on infection prevention and control and vaccine development Practitioners providing their insights on clinical practice and pharmaceutical production An accompanying website incorporating teaching resources Hugo and Russell s Pharmaceutical Microbiology, 9th edition promises to remain the essential text for pharmacy and medical students, as well as researchers and industry professionals.

Hugo & Russell's Pharmaceutical MicrobiologyDiscover the very latest developments in pharmaceutical microbiology in the 9th edition of this popular textbookMicrobiology is one of the essential pharmaceutical sciences upon which the study and practice of pharmacy is built. It has a bearing on all aspects of the manufacture of medicines and sterile products, from their design and development to their delivery as quality products. Few interventions are more central to modern medicine than the treatment of infection, where antibiosis, vaccination and hygienic practices have essential roles to play. The COVID-19 pandemic, the appearance of new pathogens and the rise of antibiotic resistance have demonstrated most completely the need for pharmaceutical practitioners, researchers and industrial scientists to be fully conversant with this field.The 9th edition of Hugo and Russell's Pharmaceutical Microbiology has been updated to meet this need. Having long served as the sole comprehensive textbook covering this subject, it has now been adapted to a critical new period in the advancement of medical and pharmaceutical research and development. Its experienced editors have incorporated contributions from subject experts and created a text which will serve the next generation of pharmacy students, pharmaceutical industry scientists and researchers.In this ninth edition of Hugo and Russell's Pharmaceutical Microbiology, readers will find:* A mix of established and new authors bringing practical and research experience to their chapters* Material covering the fundamentals of microbiology, microbial behavior and laboratory investigation* Revised chapters incorporating new material on microbe-host interactions, antibiotic resistance, emerging pathogens, public health microbiology, healthcare-associated infection and pharmaceutical manufacture* Emerging understandings from the COVID-19 pandemic on infection prevention and control and vaccine development* Practitioners providing their insights on clinical practice and pharmaceutical production* An accompanying website incorporating teaching resourcesHugo and Russell's Pharmaceutical Microbiology, 9th edition promises to remain the essential text for pharmacy and medical students, as well as researchers and industry professionals.

Notes on Contributors viiPreface to the First Edition ixPreface to the Ninth Edition xAbout the Companion Website xiPart 1 Introducing Pharmaceutical Microbiology 11 Introduction to Pharmaceutical Microbiology 3Brendan F. Gilmore and Stephen P. DenyerPart 2 Biology of Microorganisms 112 Fundamental Features of Microbiology 13Norman Hodges and Stephen P. Denyer3 Bacteria 27David Allison4 Fungi 47Kevin Kavanagh5 Viruses and Other Acellular Infectious Agents: Characteristics and Control 63Timofey Skvortsov and Jean-Yves Maillard6 Protozoa 98Tim PagetPart 3 Pathogens and Host Response 1217 Principles of Microbial Pathogenicity and Epidemiology 123David Allison and Andrew J. McBain8 Microbial Biofilms: Consequences for Health 135Brendan F. Gilmore9 Immunology 147Mark Gumbleton and Mathew W. Smith10 Vaccination and Immunisation 174Gavin J. Humphreys and Andrew J. McBainPart 4 Prescribing Therapeutics and Infection Control 19111 Antibiotics and Synthetic Antimicrobial Agents: Their Properties and Uses 193Brendan F. Gilmore12 Mechanisms of Action of Antibiotics and Synthetic Anti-infective Agents 232Peter Lambert13 Bacterial Resistance to Antibiotics 249Brendan F. Gilmore and Stephen P. Denyer14 Clinical Uses of Antimicrobial Drugs 272Hayley Wickens and Conor Jamieson15 Antibiotic Prescribing and Antimicrobial Stewardship 289Rebecca Craig16 Infection Prevention and Control: Healthcare-associated Infection 304Elaine Cloutman-GreenPart 5 Contamination and Contamination Control 32117 Microbial Spoilage, Infection Risk and Contamination Control 323Rosamund M. Baird18 Chemical Disinfectants,Antiseptics and Preservatives 343Sean P. Gorman and Brendan F. Gilmore19 Laboratory Evaluation of Antimicrobial Agents 365Brendan F. Gilmore and Sean P. Gorman20 Microbicides: Mode of Action and Resistance 385Stephen P. Denyer and Jean-Yves Maillard21 Sterilisation Procedures and Sterility Assurance 403Alistair K. Brown and Stephen P. DenyerPart 6 Pharmaceutical Production 43322 Sterile Pharmaceutical Products and Principles of Good Manufacturing Practice 435Tim Sandle23 The Manufacture and Quality Control of Immunological Products 462Tim Sandle24 Recombinant DNA Technology 480Miguel Cámara and Stephan HeebPart 7 Current Trends and New Directions 50725 The Wider Contribution of Microbiology to the Pharmaceutical Sciences 509Mathew W. Smith, James C. Birchall and Sion A. Coulman26 Alternative Strategies to Antibiotics: Priorities for Development 529Brendan F. GilmoreIndex 544