This is a book about using the best evidence to inform treatment decisions for people with cancer. It is written by oncologists for oncologists, using examples throughout to illustrate key points. The book starts off with a "e;toolbox"e; section, written in a way which will help those relatively new to the principles of evidence-based oncology to understand the key issues, and equip them with the basics of how to tell a good study from a bad one. The majority of the book then deals with an evidence-based summary of the common and important cancers in a structured and easy to read format around common patient scenarios and frequently asked questions. Whilst most of the evidence is based on randomised controlled trials, other studies are cited where appropriate eg when discussing adverse events. The unique accompanying book website will contain updates of new chapters and studies as they become available. Written by leading world figures in the evidence-based movement Includes free CD-ROM with PC eBook and sample PDA chapter Methodology of reviewing and appraising evidence discussed in the context of cancer management Clinical sections covering prevention and screening Chapters on treatment of the individual major cancers review the current best available evidence to most frequently asked questions Rigorously structured explicit searches, evidence of efficacy and harms, plus comment around clinical scenarios Free-access update website keeping the text current and live: evidbasedoncology.com

This is a book about using the best evidence to inform treatmentdecisions for people with cancer. It is written by oncologists foroncologists, using examples throughout to illustrate key points.The book starts off with a "toolbox" section, written in a waywhich will help those relatively new to the principles ofevidence-based oncology to understand the key issues, and equipthem with the basics of how to tell a good study from a bad one.The majority of the book then deals with an evidence-based summaryof the common and important cancers in a structured and easy toread format around common patient scenarios and frequently askedquestions. Whilst most of the evidence is based on randomisedcontrolled trials, other studies are cited where appropriate egwhen discussing adverse events. The unique accompanying bookwebsite will contain updates of new chapters and studies as theybecome available.* * Written by leading world figures in the evidence-basedmovement* Includes free CD-ROM with PC eBook and sample PDA chapter* Methodology of reviewing and appraising evidence discussed inthe context of cancer management* Clinical sections covering prevention and screening* Chapters on treatment of the individual major cancers reviewthe current best available evidence to most frequently askedquestions* Rigorously structured explicit searches, evidence of efficacyand harms, plus comment around clinical scenarios* Free-access update website keeping the text current and live:evidbasedoncology.com

Contributors.Preface.Abbreviations.Levels of Evidence and Grades of Recommendation.Section I: Principles and Practice of "Critical Appraisal".Section II: Cancer Prevention.Section III: Screening for Cancers.Section IV: Treating Tumours of the Respiratory System.Section V: Treating Gastrointestinal System.Section VIII: Treating Breast Cancer.Section IX: Treating Skin Cancer.Section X: Treating Sarcomas.Section XI: Treating Central Nervous System Tumours.Section XIII: Treating Cancers of the Eye and AssociatedStructures.Index.