Salim Yusuf , Professor of Medicine, Heart and Stroke Foundation Chair in Cardiology, and Director of the Population Health Research Institute, McMaster University, Hamilton, Ontario.
John Cairns Dean , Faculty of Medicine, University of British Columbia.

John Camm , Professor of Clinical Cardiology and Head of the Department of Cardiac & Vascular Sciences at St George s, University of London.

Ernest Fallen , Professor Emeritus in Cardiology and Tutor in Cardiology Residency Program, McMaster University, Hamilton, Ontario.

Bernard Gersh , Professor of Medicine, Department of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota.

List of contributors, viii
Preface to the third edition, xiv

Classification of recommendations and levels of evidence, xvi

List of abbreviations, xvii

Part I: General concepts and critical appraisal
Salim Yusuf, Editor

1 Evidence-based decision making: patient-physician interface, 3
Philip J Devereaux, Marc Pfeffer, Salim Yusuf

2 Obtaining incremental information from diagnostic tests, 14
Raymond J Gibbons

3 Clinical trials and meta-analysis, 26
Jonathan R Emberson, Colin Baigent

4 Understanding concepts related to health economics, 38
Mark A Hlatky

5 Major vascular complications in patients undergoing non-cardiac surgery: magnitude of the problem, risk prediction, surveillance, and prevention, 47
Philip J Devereaux, Matthew Chan, John Eikelboom

6 Implementing evidence-based medicine in cardiology, 63
Brahmajee K Nallamothu, Thomas T Tsai, Jack V Tu

7 The application of evidence-based medicine to employment fitness standards: the transportation industries with special reference to aviation, 79
Michael Joy

Part II: Prevention of cardiovascular diseases
Salim Yusuf and John A Cairns, Editors

8 Global perspective on cardiovascular disease, 95
K Srinath Reddy

9 Avoidance of worldwide vascular deaths and total deaths from smoking, 111
Prabhat Jha, Prem Mony, James Moore, Witold Zatonski

10 Tobacco and cardiovascular disease: achieving smoking cessation in cardiac patients, 125
Andrew Pipe

11 Lipids and cardiovascular disease, 138
Malcolm Law

12 Use of lipid-lowering agents in the prevention of cardiovascular disease, 147
R Alan Failor, Jeffrey L Probstfi eld

13 Blood pressure and cardiovascular disease, 165
Curt D Furberg, Bruce M Psaty, Elsayed Z Soliman

14 Dysglycemia and the risk of cardiovascular events, 179
Hertzel C Gerstein, Zubin Punthakee

15 Physical activity and exercise in cardiovascular disease prevention and rehabilitation, 190
Ray W Squires

16 Psychosocial factors, 201
Annika Rosengren

17 The social determinants of cardiovascular disease, 211
Martin McKee, Clara K Chow

18 Obesity, 221
Raj S Padwal, Arya M Sharma

19 Ethnicity and cardiovascular disease, 235
Clara K Chow, Sonia S Anand, Salim Yusuf

20 Fetal origins of coronary artery disease, 258
Katherine M Morrison, Stephanie Atkinson, Koon K Teo

21 Genetics of coronary heart disease, 268
Michael S Cunnington, Bernard D Keavney

22 Molecular genetics of cardiovascular disorders, 288
Ali J Marian, Robert Roberts

23 Diet and cardiovascular disease, 304
K Srinath Reddy

24 Integrating approaches to prevention of cardiovascular disease, 328
David A Wood, Kornelia Kotseva

Part IIIa: Stable coronary artery disease
John A Cairns and Bernard J Gersh, Editors

25 Medical management of stable coronary artery disease, 345
William E Boden

26 Percutaneous intervention, 357
David A Wood, Rohit Khurana, Christopher E Buller

27 Surgical coronary artery revascularization, 379
Morgan L Brown, Thoralf M Sundt III

28 Comparisons of percutaneous coronary intervention and coronary artery bypass grafting, 392
Arashk Motiei, Thoralf M Sundt III, Charanjit S Rihal

Part IIIb: Acute coronary syndromes
John A Cairns and Bernard J Gersh, Editors

29 Non-ST segment elevation acute coronary syndromes: unstable angina and non-ST segment elevation myocardial infarction, 409
Pierre Theroux, John A Cairns

30 Early prehospital management of ST segment elevation myocardial infarction, 444
Robert C Welsh, Paul W Armstrong

31 Reperfusion therapies for ST segment elevation myocardial infarction, 456
Joseph B Muhlestein, Jeffrey L Anderson

32 Antithrombotic therapies for patients with ST segment elevation myocardial infarction, 475
Andrew J Lucking, Keith A A Fox

33 Complications after myocardial infarction, 495
Peter L Thompson

34 An integrated approach to the management of patients after the early phase of ST segment elevation myocardial infarction, 516

Evidence based Cardiology was first published in 1998 to universal acclaim. Now, with the move towards more patient focused health care and at the same time increased emphasis on health economics, evidence-based practice is a more important force in health care delivery than ever.
This new third edition, written by the world's leading cardiologists, provides graded evidence-based reviews of the major trials together with recommendations for optimum management, and now includes new grading and recommendation methodology.

This is a unique book in the field of cardiology, and the largest evidence based clinical cardiology text.