Proceedings from the first International Symposium on Primo Vascular System 2010 (ISPS 2010) with special topics on cancer and regeneration was held in Jecheon, Korea during September 17-18, 2010. Includes coverage of new study results that have better revealed the functional aspects of PVS, including its roles in the areas of regenerative medicine and cancer.

Preface                                                        

Organization of ISPS2010                                           

Sponsorship                                                        

Acknowledgements                                                    

Part I: Past, Present and Future of Primo Vascular System Research

1.  A Brief History of the Bong-Han Theory and the Primo Vascular System
Kwang-Sup Soh

2.  Summary of Bong-Han Kim’s Publications
Jungdae Kim, Jonghyun Jung, Michael Potroz

3.  Follow-up Study on the Morphological Characteristics in Bong-Han Theory: an Interim Report
Satoru Fujiwara, Sun-Bong Yu

4.  Recollection of Early Research on Primo Vascular System: Ultimate Implication of Bong-Han Theory
Jong-Su Lee

5.  Current State of Research on the Primo Vascular System
Kwang-Sup Soh

6.  Primo Vascular System Basic and Applied Research Outline
Michael Potroz, Kwang-Sup Soh

7.  The Primo Vascular System: Facts, Open Questions and Future Perspectives
David Harrison, Peter Vaupel

Part II: Primo Vascular System in Various Organs

8.  Structure of the Sinus in the Primo Vessel inside the Bovine Cardiac Chambers
Byung-Cheon Lee, Hong Bae Kim, Baeckkyoung Sung, Ki Woo Kim, Jamin Sohn, Boram Sohn, Byung-Joon Chang, Kwang-Sup Soh

9.  Finding a Novel Threadlike Structure on the Intra-abdominal Organ Surface of Small Pigs by Using In-vivo Trypan Blue Staining
M. Hossein Ayati, Tian Yu-ying, Huang Tao, Zhang Yu-Qing，Che Yong-Zhe, Zhang Wei-Bo

10. Observation of Primo Vascular System on Intestinal Fascia of Dogs
Zhaofeng Jia, Kwang-Sup Soh, Qiang Zhou, Bo Dong, Wenhui Yu

11. Development of the Putative Primo Vascular System before the Formation of Vitelline Vessels in Chick Embryos
Byung-Cheon Lee, Seung-Yoon Lee, Kwang-Sup Soh, Gil-Ja Ghon

12. Characterization of Primo Nodes and Vessels by High Resolution Light Microscopy
Vitaly Vodyanoy

13. Distribution of Primo Vessels in the Mesentery of a Mouse
Zhendong Su, Ping An, Jeong-No Lee, Kwang-Sup Soh

15. Comparison of the Primo Vascular System with a Similar-looking Structure
Cheon-Joo Choi, Chae-Hun Leem

16. Effect of the Primo Vascular System on Liver Tissue Recovery after Irreversible Electroporation: a Preliminary Study
Hong-Bae Kim, Chang-Kyu Sung, Saeyoung Ahn

17. Detection of the Primo Vessels in the Rodent Thoracic Lymphatic Ducts
Inho Choi, Hee-Kyoung Jeong, Young-Kwon Hong

18. Histological Comparison of Primo Nodes in Abdominal Membrane and Lymph Nodes of Rat
Kyoung-Hee Bae, Zhendong Su, Kwang-Sup Soh, Hee Min Kwon

19. Visualization of the Primo Vascular System by Using Trypan Blue in the Subarachnoid Space of Rats
Inhyung Lee, Zhen-dong Su, Ki Woo Kim, Byung-Cheon Lee, Kwang-Sup Soh

20. Network of the Primo Vascular System in the Rat Hypodermis
Byung-Cheon Lee, Zhendong Su, Baeckkyoung Sung, Ki Woo Kim, Jin-Myung Cha, Jin-Kyu Lee, Byung-Joon Chang, Kwang-Sup Soh

Part III: Primo Microcell (SanAl) and Stem Cells

21. Identification and Characterization of Small Stem-like Cells in the Primo Vascular System of Adult Animals
Vyacheslav Ogay, Kwang-Sup Soh

22. Membrane Mechanical Property of Primo Microcells
Ku Youn Baik, Chang Ho Kim, Suk Yi Woo, Sae Chae Jeoung, Kwang-Sup Soh

23. Primo microcell in a Primo Node as a Possible Origin of Adult Stem Cells
Seong-hun Ahn, Sung-won Lee, Sung-Yeoun Hwang, Jae-hyo Kim, In-chul Sohn

24. Budding Primo Microcells (Sanals) in a Culture Medium with Fertilized Egg Albumen and RPMI Medium
Byung-Cheon Lee, Dae-In Kang, Kwang-Sup Soh

Part IV: Cancer

25. Identification of Primo Vascular System in Murine Tumors and Viscera
Walter Akers, Yang Liu, Gail Sudlow, Joon Lee, Jung Sun Yoo, Byung-Cheon Lee, Kwang-Sup Soh, Samuel Achilefu

26. Molecular Compositional Differences of Primo and Lymphatic Vascular System in Murine Melanoma Models
Jung Sun Yoo, Baatartsogt Oyungerel, Il Young Han, Ji Young Kim, ChoongHwan Lee, Kang Duk Choi, Kwang-Sup Soh, Tae Young Han

27. Using Human Observations to Gain Biologic Insights and New Treatments
Donald M. Miller, Shelia D. Thomas, Kara Sedoris, Ashraful Islam, David Muench, Cortney Clarkson, Charles A. Koller

28. Translational Development of Therapeutic Vaccines for Lymphoma
Larry W. Kwak

29. Oxygen Transport to Tumors: Pathophysiology and Clinical Implications
Peter Vaupel

30. Stress Responses of Pancreatic Cancer Cells and Their Significance in Invasion and Metastasis
Yoshiharu Motoo, Qi-Sheng Xia, Naoki Nakaya, Takeo Shimasaki, Hideo Nakajima, Yasuhito Ishigaki

31. Human Urine Extract (CDA-2) Eliminates Cancer Stem-Like Cells and Inhibits Metastasis-Its Potential Role on the Microenvironment of Primo Vascular System
Chih-Jung Yao, Ping-Hsiao Shih, Chi-Tai Yeh, Gi-Ming Lai

Part V: Imaging, Oxygen, Physiology and Others

32. Mapping PVS by Molecular Imaging with Contrast Agents
Kyung A. Kang

33. Unusual Optical Properties of Collagen and Implications for the Primo Vascular System
Eduard van Wijk, Margo Groeneveld, Jan van der Greef, Roeland van Wijk

34. Basic Electrophysiological Properties of Cells in the Organ Surface Primo Vascular Tissues of Rats
Jae-Hong Choi, Tae Hee Han, Chae Jeong Lim, So Yeong Lee, Pan Dong Ryu

35. Effects of Cholinergic Drugs on Membrane Potential of Cells in Organ Surface Primo Nodes
Sang-Hyun Park, Byung-Cheon Lee, Cheon-Joo Choi, Kwang-Sup Soh, Pan Dong Ryu

37. PKA Activation in Cardiac Myocytes Affects the Voltage Dependence of Na-K ATPase Pump and Na-Ca Exchange Currents Differently
Chin Ok Lee, David C. Gadsby

38. Bioimaging of Stem Cells, Live Tissue and Whole Animals using Diversity Oriented Fluorescence Library Approach
Young-Tae Chang

39. The Clinical Application of Optical Spectroscopy in Monitoring Tissue Oxygen Supply Following Cancer Treatment
David K Harrison

Part VI: Acupuncture

40. Oriental Medicine in Japan, Lymphology and Primo Vascular System
Moriya Ohkuma

41. From the Anatomical Discovery of Meridians and Collaterals to Fasciaology Theory
Yu Bai, Lin Yuan, Yong Huang, Chun-lei Wang, Jun Wang, Jin-peng Wu, Jing-xing Dai, Dong-fei Li, Chun Yang, Mei-chun Yu, Hui-ying Yang, Hui Tao, Ou Sha, David Tai Wai Yew

42. An Evidence-based Review of Acupuncture as an Adjunctive Therapy in Comprehensive Cancer Care
Christopher Zaslawski

43. Thermal Characteristics of Moxibustion and its Implication to Primo Vascular System
Seung-Ho Yi, Moo-Won Park, Hye-Jung Lee