As prevalent as anxiety is as a diagnosis, clinically complex cases are even more so. At the same time that it is recognized as a spectrum of disorders with many possibilities for intervention, it is most often seen with variations that further complicate treatment.

The Handbook of Treating Variants and Complications in Anxiety Disorders explains in clear detail how and why clinical factors present challenges to clinicians treating clients with these disorders. Comorbid conditions often found in children, adolescents, and adults with anxiety, including developmental disabilities and personality disorders, are analyzed in the context of treatment. Case examples and literature reviews illustrate the relative merits of integrated versus sequential treatment, the importance of prioritizing behaviors, age-related considerations, and therapist issues. This best-practices approach guides readers in choosing current evidence-based options for treatment that is tailored to the individual and effective in the short and long term. Included in the Handbook:

• Prognostic indicators of treatment response for children and adults with anxiety disorders.
• Treatment of comorbid anxiety and disruptive behavior in youth.
• Treatment of PTSD with comorbid borderline personality disorder.
• Limited motivation, patient-therapist mismatch, and the therapeutic alliance.
• Assessment and treatment of comorbid anorexia nervosa and obsessive compulsive disorder.
• Treatment of comorbid anxiety disorders across the lifespan.

Developed as a companion reference to the Handbook of Assessing Variants and Complications in Anxiety Disorders, the Handbook of Treating Variants and Complications in Anxiety Disorders is of immediate relevance to researchers, scientist-practitioners, and graduate students in clinical child, school, and developmental psychology; social work; psychiatry; psychotherapy; counseling; and pediatrics.

Section I: Overview of Complexities in Anxiety Disorders.- Chapter 1: Nature and Etiological Models of Anxiety Disorders.- Chapter 2: Prognostic Indicators of Treatment Response for Adults with Anxiety.- Chapter 3: Prognostic Indicators of Treatment Response for Children with Anxiety Disorders.- Chapter 4: Continuing to Advance Empirically-Supported Treatments: Factors in Empirically-Supported Practice for Anxiety Disorders.- Section II: Complexities in Childhood and Adolescent Anxiety Disorders.- Chapter 5: Treatment of Childhood Anxiety in Autism Spectrum Disorders.- Chapter 6: Treatment of Comorbid Anxiety and Disruptive Behavior in Youth.- Chapter 7: Diagnosis and Cognitive Behavioral Treatment of Anxiety Disorders in Young Children.- Chapter 8: Treating Obsessive-Compulsive Disorder in the Very Young Child.- Chapter 9: Treatment of Childhood Tic Disorders with Comorbid OCD.- Chapter 10: Treatment of Childhood Anxiety in the Context of Limited Cognitive Functioning.- Chapter 11: Special Considerations in Treating Anxiety Disorders in Adolescents.- Chapter 12: Social Anxiety and Socialization Among Adolescents.- Chapter 13: PANDAS: Immune Related OCD.- Section III: Complexities in Adult Anxiety Disorders.- Chapter 14: Treatment of Posttraumatic Stress Disorder with Comorbid Borderline Personality Disorder: Integrating Dialectical Behavior Therapy and Prolonged Exposure.- Chapter 15: Treatment of Anxiety and Comorbid Cluster A Personality Disorders.- Chapter 16:  Treatment of Comorbid Depression.- Chapter 17: Limited Motivation, Patient-Therapist Mismatch, and the Therapeutic Alliance.- Chapter 18: Substance Abuse and Anxiety Disorders: The Case of Social Anxiety Disorder and PTSD.- Section IV: Cross Developmental Complexities.- Chapter 19: Treatment of Comorbid Anxiety Disorders across the Lifespan.- Chapter 20: Family Conflict and Childhood Anxiety.- Chapter 21: Assessment and Treatment of Comorbid Anorexia Nervosa and Obsessive Compulsive Disorder.- Chapter 22: Cluster C Personality Disorders and Anxiety Disorders.- Chapter 23: Therapist Barriers to the Dissemination of Exposure Therapy.- Chapter 24: Harnessing the Web: Internet and Self-Help Therapy for People with Obsessive-Compulsive Disorder and Post-Traumatic Stress Disorder.- Chapter 25: Where Do We Go From Here? How Addressing Clinical Complexities Will Result in Improved Therapeutic Outcomes.