In its first edition, Principles of Clinical Medicine for Space Flight established itself as the authoritative reference on the contemporary knowledge base of space medicine and standards of care for space flyers. It received excellent notices and is used in the curricula of civilian and military training programs and used as a source of questions for the Aerospace Medicine Certifying Examination under the American Board of Preventive Medicine. 

In the intervening few years, the continuous manning of the International Space Station has both strengthened existing knowledge and uncovered new and significant phenomena related to the human in space.  The Second Edition incorporates this information. Gaps in the first edition will be addressed with the addition new and revised chapters. This edition is extensively peer reviewed and represents the most up to date knowledge.

Foreword to the First Edition.- Preface to the First Edition.- Foreword.- Preface.- Contributors.- Part I. Unique Attributes of Space Medicine.- 1. Physical and Bioenvironmental Aspects of Human Space Flight.- 2. Radiation and Radiation Disorders.- 3. Hypoxia, Hypercarbia, and Atmospheric Control.- 4. Health Effects of Atmospheric Contamination.- 5. Acoustic and Auditory Issues in Principles of Clinical Medicine for Space Flight.- 6. Spaceflight Medical Systems.- 7. Surgical Capabilities.- 8. Telemedicine.- 9. Diagnostic Imaging in Space Medicine.- 10. Medical Evacuation Risk and Crew Transport.- Part II. Spaceflight Clinical Medicine.- 11. Medical Evaluations and Standards.- 12. Human Response to Space Flight.- 13. Spaceflight Metabolism and Nutritional Support.- 14. Space and Entry Motion Sickness.- 15. Acute Care.- 16. Decompression Related Disorders.- 17. Medical Aspects of Extravehicular Activity.- 18. Renal and Genitourinary Concerns.- 19. Musculoskeletal Response to Space Flight.- 20. Physical Performance, Countermeasures, and Postflight Reconditioning.- 21. Immunology and Microbiology.- 22. Cardiovascular Aspects of Space Flight.- 23. Neurologic Concerns.- 24. Gynecologic and Reproductive Considerations.- 25. Behavioral Health and Performance Support.- 26. Sleep, Circadian Rhythms, and Fatigue Management in Spaceflight Operations.- 27. Spaceflight Pharmacology.- 28. Ophthalmologic Concerns.- 29. Dental Considerations.- 30. Spacecraft Accident Investigation.- Index.