State-of-the-art reviews covering major aspects of antibodies and intervention against infectious diseases The connection between antibodies and infectious diseases has spawned entire related fields of study. Antibodies for Infectious Diseases presents perspectives from leading research scientists and summarizes the amazing progress in this area into a single definitive source. Providing a broad survey of the most important aspects of the field of antibodies for infectious diseases, this book presents general features pertaining to structure, function, isotype, and the role of complement in antibody function examines the role of antibodies in antimicrobial immunity with specific targets details new methods for expression of monoclonal antibodies, in plants or by transfer of antibody genes for in vivo expression in treated subjects Antibodies for Infectious Diseases is a comprehensive reference for researchers, pharmaceutical developers, and health care professionals on the status of the development of antibody-based therapies for treating infectious diseases. It is also useful as supplemental reading for upper level life sciences students. If you are looking for online access to the latest clinical microbiology content, please visit wiley.com/learn/clinmicronow.

State-of-the-art reviews covering major aspects of antibodies and intervention against infectious diseasesThe connection between antibodies and infectious diseases has spawned entire related fields of study. Antibodies for Infectious Diseases presents perspectives from leading research scientists and summarizes the amazing progress in this area into a single definitive source.Providing a broad survey of the most important aspects of the field of antibodies for infectious diseases, this book* presents general features pertaining to structure, function, isotype, and the role of complement in antibody function* examines the role of antibodies in antimicrobial immunity with specific targets* details new methods for expression of monoclonal antibodies, in plants or by transfer of antibody genes for in vivo expression in treated subjectsAntibodies for Infectious Diseases is a comprehensive reference for researchers, pharmaceutical developers, and health care professionals on the status of the development of antibody-based therapies for treating infectious diseases. It is also useful as supplemental reading for upper level life sciences students.If you are looking for online access to the latest clinical microbiology content, please visit wiley.com/learn/clinmicronow.

ContributorsPrefaceIntroduction1 History and Practice: Antibodies in Infectious DiseasesGeneral Features of Immunoglobulins2 Functions of Antibodies3 Antibody Structure4 The Role of Complement in Antibody Therapy for Infectious Diseases5 Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and TreatmentAntibody Discovery Approaches6 Phage and Yeast Display7 Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells8 Use of Human Hybridoma Technology To Isolate Human Monoclonal Antibodies9 Humanized Mice for Studying Human Immune Responses and Generating Human Monoclonal Antibodies10 Antibodies: Computer-Aided Prediction of Structure and Design of FunctionPathogen-Specific Antibodies11 Antibodies Targeting the Envelope of HIV-112 Committing the Oldest Sins in the Newest Kind of Ways--Antibodies Targeting the Influenza Virus Type A Hemagglutinin Globular Head13 Prevention of Respiratory Syncytial Virus Infection: From Vaccine to Antibody14 Human Metapneumovirus15 Dengue Antibody-Dependent Enhancement: Knowns and Unknowns16 Immunotherapeutic Approaches To Prevent Cytomegalovirus-Mediated Disease17 Rotavirus18 Bacterial Toxins--Staphylococcal Enterotoxin BTechnical Advances19 Antibody Engineering20 High-Throughput DNA Sequencing Analysis of Antibody Repertoires21 Antibody Informatics: IMGT, the International ImMunoGeneTics Information System Strains22 Probing Antibody-Antigen Interactions23 Radiolabeled Antibodies for Therapy of Infectious DiseasesAlternate Systems for Expression24 Plant-Derived Monoclonal Antibodies for Prevention and Treatment of Infectious Disease25 Vector-Mediated In Vivo Antibody ExpressionIndex