Beschreibung:
Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice is the first book that provides comprehensive coverage of the three most important themes in the field of EDC research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians' office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.
This book provides comprehensive coverage of the three most important themes in the field of Endocrine Disrupting Chemicals (EDC) research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs.
Contents Preface Contributors Part I. The Basic Biology of Endocrine Disruption 1. Introduction to Endocrine-disrupting Chemicals Andrea C. Gore 2. Endocrine Disruption and the Female Ana M. Soto, Beverly S. Rubin, and Carlos Sonnenschein 3. Endocrine Disruption in the Male Prue A. Cowin, Paul M.D. Foster, and Gail P. Risbridger 4. Endocrine Disruption and the Brain Deena M. Walker and Andrea C. Gore 5. Heavy Metals as Endocrine-disrupting Chemicals Cheryl A. Dyer 6. Cellular Mechanisms of Endocrine Disruption: Traditional and Novel Actions Stuart R. Adler 7. Endocrine Disruptors, Epigenetically Induced Changes, and Transgenerational Transmission of Characters and Epigenetic States Carlos Guerrero-Bosagna and Luis Valladares Part II. The Biology of EDCs in Humans 8. Implications of Thyroid Hormone Signaling through the Phosphoinositide-3 Kinase for Xenobiotic Disruption of Human Health David L. Armstrong 9. Endocrine Disruption and Reproductive Outcomes in Women Sarah Janssen, Victor Y. Fujimoto, and Linda C. Giudice 10. Epidemiologic Evidence on the Relationship between Environmental Endocrine Disruptors and Male Reproductive and Developmental Health Russ Hauser, Julia S. Barthold, and John D. Meeker 11. Human Exposures and Body Burdens of Endocrine-disrupting Chemicals Antonia M. Calafat and Larry L. Needham Part III. Implications and Mitigations of EDCs 12. Policy Implications of Endocrine-disrupting Chemicals in Humans Tracey J. Woodruff 13. Talking with Patients and the Public about Endocrine-Disrupting Chemicals Gina Solomon and Sarah Janssen 14. Community Interventions to Reduce Exposures to Chemicals with Endocrine Disrupting Properties Barbara Brenner and Maida Galvez 15. What can we do about Endocrine-Disrupting Chemicals? Joseph Thornton
Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice is the first book that provides comprehensive coverage of the three most important themes in the field of EDC research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians’ office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.
