This volume surveys data describing the role of free radicals and antioxidants in clinical and pre-clinical trials, and describes basic women's health research, including hypertension and cardiovascular disease, osteoporosis, obesity and restless leg syndrome.

This volume covers data describing the role of free radicals and antioxidants that deal with clinical and pre-clinical trials, as well as basic research in the area of women's health.  There is increasing evidence that oxidative stress is a causative, or at least a supporting factor in female pathology and infertility.  During advancing gestational age, oxidative stress biomakers rise.  Oxidative stress plays a regulatory role in transcription, signal transduction, gene expression and membrane trafficking.  A search on Pub Med shows 449 papers have been published to date related to women's health disorders and use of antioxidants in a variety of disease that are prevalent in women, such as hypertension and cardiovascular disease, osteoporosis, obesity and restless leg syndrome.