The neglected tropical diseases (NTDs) are among the most common infections of the world s poorest people and have profound ramifications on affected populations, including physical, mental, social, and economic. This third edition of Forgotten People, Forgotten Diseases coincides with the third decade of the NTDs movement, which has given access to essential NTD preventative treatments and medications to more than 1 billion people. Professor Peter Hotez, MD, PhD, one of the founders of the NTD movement, discusses how the NTD space evolved and control was implemented against these ancient scourges, through alliances between nongovernmental development organizations and private-public partnerships. Forgotten People, Forgotten Diseases also Reports on the health and economic effects of the NTDs, and the challenges of measuring diseases that do not always kill, but adversely affect productivity, child development, pregnancy outcome, and economic development. Lays a roadmap for continued control of existing and newly identified NTDs and spotlights potential opportunities for reducing global poverty and repairing the world. Describes a global initiative to provide annual mass drug administration for more than one billion people affected by NTDs. Highlights the role of innovation and product development partnerships for new treatments and vaccines. Explains how science and vaccine diplomacy ensure that a new generation of biotechnologies reaches the world s poorest people. Forgotten People, Forgotten Diseases remains an essential resource for anyone seeking insight into global advocacy coordination and mobilization of resources to combat NTDs and continues to tell the story of the world s people who live in extreme poverty and what it means for them to live with these devastating diseases. Like Dr. Hotez, I have struggled with how to best get the word out about our need to address NTDs and their link to poverty. Now he has provided us all with a remarkable tool, a book for people without an extensive scientific or medical background. Forgotten People, Forgotten Diseases is an excellent one-stop primer about NTDs. Soledad O Brien, Host, Matter of Fact with Soledad O Brien

The neglected tropical diseases (NTDs) are among the most common infections of the world's poorest people and have profound ramifications on affected populations, including physical, mental, social, and economic. This third edition of Forgotten People, Forgotten Diseases coincides with the third decade of the NTDs movement, which has given access to essential NTD preventative treatments and medications to more than 1 billion people.Professor Peter Hotez, MD, PhD, one of the founders of the NTD movement, discusses how the NTD space evolved and control was implemented against these ancient scourges, through alliances between nongovernmental development organizations and private-public partnerships. Forgotten People, Forgotten Diseases also* Reports on the health and economic effects of the NTDs, and the challenges of measuring diseases that do not always kill, but adversely affect productivity, child development, pregnancy outcome, and economic development.* Lays a roadmap for continued control of existing and newly identified NTDs and spotlights potential opportunities for reducing global poverty and "repairing the world."* Describes a global initiative to provide annual mass drug administration for more than one billion people affected by NTDs.* Highlights the role of innovation and product development partnerships for new treatments and vaccines.* Explains how science and vaccine diplomacy ensure that a new generation of biotechnologies reaches the world's poorest people.Forgotten People, Forgotten Diseases remains an essential resource for anyone seeking insight into global advocacy coordination and mobilization of resources to combat NTDs and continues to tell the story of the world's people who live in extreme poverty and what it means for them to live with these devastating diseases."Like Dr. Hotez, I have struggled with how to best get the word out about our need to address NTDs and their link to poverty. Now he has provided us all with a remarkable tool, a book for people without an extensive scientific or medical background. Forgotten People, Forgotten Diseases is an excellent 'one-stop' primer about NTDs."--Soledad O'Brien, Host, Matter of Fact with Soledad O'Brien

Preface ixAcknowledgments xiiiChapter 1 Introduction to the Neglected Tropical Diseases: the Ancient Afflictions of Stigma and Poverty 1Chapter 2 "The Unholy Trinity": the Soil-Transmitted Helminth Infections Ascariasis, Trichuriasis, and Hookworm Infection 17Chapter 3 Schistosomiasis (Snail Fever) and the Food-borne Trematodiases 39Chapter 4 Elephantiasis: Lymphatic Filariasis, Endemic Nonfilarial Elephantiasis (Podoconiosis), and Dracunculiasis (Guinea Worm) 55Chapter 5 The Blinding Neglected Tropical Diseases: Onchocerciasis (River Blindness) and Trachoma 75Chapter 6 The Mycobacterial Infections: Buruli Ulcer and Leprosy 95Chapter 7 The Kinetoplastid Infections: Human African Trypanosomiasis (Sleeping Sickness), American Trypanosomiasis (Chagas Disease), and the Leishmaniases 111Chapter 8 The Urban Neglected Tropical Diseases: Leptospirosis, Dengue and Zika, and Rabies 143Chapter 9 The Neglected Tropical Diseases of North America 159Chapter 10 Uniting to Combat Neglected Tropical Diseases, and a New WHO Roadmap (2021-2030) 181Chapter 11 Future Trends in Control of Neglected Tropical Diseases and the Antipoverty Vaccines 203Chapter 12 The Newest NTDs and a Plea to "Repair the World" 217Appendix: What Are the Neglected Tropical Diseases? 227Index 229About the Author 239