If you could learn with precision the exact day of your death, even if it were years into the future, would you want to know? At first glance, the untimely death of renowned Brazilian mathematician Eduardo Rodriguez appears to be of natural causes-he died of a heart attack in his sleep, with his wife by his side-but when it's discovered that he had liquidated his assets, organized his estate and even arranged his own funeral, questions start to arise. Halfway around the world in Rhode Island, 32-year-old Caroline Stanley hadn't been feeling well for weeks. She and her husband, Ron, were hoping the fatigue was due to a second pregnancy, but when that dream was dashed by a negative test, she headed to her doctor who diagnosed her true ailment: a rare form of leukemia. What ties these dynamic people and events together is revealed through a series of karmic events involving a kidnapping, a race through downtown Sao Paulo, a quirky priest, a look at the alluring city of Brasilia, a blossoming romance, and small-town life in Rhode Island. And what is discovered in the end could change the course of not only those involved, but that of the entire human race.