Beschreibung:
Mesothelioma is a global problem, its incidence is rising in Europe, and it is a major health problem in the USA and other parts of the world, largely related to the previous use of asbestos products. Diagnosis, which rests on the pathology, is very difficult because of its diverse appearances and the potential for other diseases to mimic it. This monograph has been assembled by an international group of experts with a wealth of experience from France, UK, USA, Australia and Canada to aid in pathological diagnosis. In all these countries, the disease poses significant health problems. This book deals with clinical, radiological, epidemiological, molecular, and histopathological aspects of the disease. Tumors of the pleural, pericardial, peritoneal cavities as well as the ovary and tunica vaginalis are considered. Differential diagnoses of serosal-based lesions are fully discussed and the use of immunohistochemical stains is explained. Plentiful illustrations give further aid to diagnosisAn essential read for all diagnostic pathologists as well as general pathologists, who are sometimes required to diagnose the disease at biopsy or post mortem. The book will be also invaluable to members of the medical and legal professions who are involved with various aspects of this disease.
• Only up-to-date title in the market
• Current topic with significant media coverage
• Internationally relevant, the use of asbestos and its consequences is a global problem
• This title aids in pathological diagnosis which is very difficult
• Contributors are experts from France, UK, USA, Australia and Canada
• Plentiful, colored illustrations complete the text
• Target group exceeds pathologists: The diagnosis is evidence for medico-legal purposes, which makes the book invaluable to members of legal profession specializing in this disease
1. The Epidemiology of Mesothelioma 2. Molecular Biology 3. Serosal Anatomy and Anatomical Distribution of Mesothelioma 4. Clinical Aspects of Mesothelioma 5. Management of Malignant Serosal Effusions 6. Pathologic Diagnosis and Classification of Mesothelioma 7. Macroscopic Features of Mesotheliomas 8. Classification and Histologic Features of Epithelioid Mesotheliomas A. Epithelioid Mesothelioma B. Biphasic Mesothelioma C. Sarcomatoid Mesothelioma D. Desmoplastic Malignant Mesothelioma E. Lymphohistiocytoid Mesothelioma 9. Differential Diagnosis: Mesothelial Proliferations A. Reactive Mesothelial Proliferations (Epithelioid) B. Fibrous Pleurisy C. Immunohistochemical Findings in Reactive vs. Neoplastic Processes 10. Differential Diagnosis: Other Mesothelial Lesions A. Adenomatoid Tumors B. Well Differentiated Papillary Mesothelioma C. Multicystic Mesothelioma 11. Non Mesothelial Lesions A. Reactive Squamous Metaplasia B. Nodular Histiocytic Mesothelial Hyperplasia C. Endosalpingiosis D. Ectopic Decidua 12. Non Mesothelial Tumors of the Serosal Cavity: Sarcomas A. Synovial Sarcoma B. Epithelioid Hemangioendothelioma and Angiosarcoma C. Leiomyosarcoma D. Malignant Peripheral Nerve Sheath Tumor E. Primitive Neuroectodermal Tumor F. Desmoid Tumor G. Desmoplastic Round Cell Tumor H. Pleuropulmonary Blastoma I. Inflammatory Myofibroblastic Tumor 13. Non Mesothelial Tumors: Other Than Sarcomas A. Solitary Fibrous Tumour B. Calcifying Fibrous Pseudotumour C. Leiomyomatosis Peritonealis Disseminata D. Thymoma/Thymic Carcinoma E. Melanoma F. Serous Carcinoma G. Lymphomas of the Serosal Cavities H. Other Lymphomas that may Involve the Pleura 14. APPENDICES
Mesothelioma is a global problem, its incidence is rising in Europe, and it is a major health problem in the USA and other parts of the world, largely related to the previous use of asbestos products. Diagnosis, which rests on the pathology, is very difficult because of its diverse appearances and the potential for other diseases to mimic it.
This monograph has been assembled by an international group of experts with a wealth of experience from France, UK, USA, Australia and Canada to aid in pathological diagnosis. In all these countries, the disease poses significant health problems. This book deals with clinical, radiological, epidemiological, molecular, and histopathological aspects of the disease. Tumors of the pleural, pericardial, peritoneal cavities as well as the ovary and tunica vaginalis are considered. Differential diagnoses of serosal-based lesions are fully discussed and the use of immunohistochemical stains is explained. Plentiful illustrations give further aid to diagnosis
An essential read for all diagnostic pathologists as well as general pathologists, who are sometimes required to diagnose the disease at biopsy or post mortem. The book will be also invaluable to members of the medical and legal professions who are involved with various aspects of this disease.
