"e;Diseases of the nervous system in infancy and childhood have a profound impact on the lives of patients and their families and are probably the most disruptive of all paediatric ailments. Aicardi's Diseases of the Nervous System in Childhood is thus the essential resource for child neurologists, neurologists, paediatricians, and physicians in developmental medicine. The third edition has been extensively updated to incorporate the tremendous volume of new information since the previous edition, but remains as clinically oriented as its predecessors. Because of the enormous and wide-ranging amount of new material available, Aicardi and his co-editors have been joined by an eminent team of international experts who have contributed many of the chapters.AUTHORS APPOINTMENTS page viiPREFACE ixPART I. NEONATAL NEUROLOGY 11. NEUROLOGICAL DISEASES IN THE PERINATAL PERIOD 3Linda de VriesPART II. CNS MALFORMATIONS, CHROMOSOMAL ABNORMALITIES, NEUROCUTANEOUS 39SYNDROMES AND SKULL MALFORMATIONS2. MALFORMATIONS OF THE CENTRAL NERVOUS SYSTEM 413. NEUROCUTANEOUS DISEASES AND SYNDROMES 1034. NEUROLOGICAL AND BEHAVIOURAL ASPECTS OF GENETIC ANOMALIES AND 137DYSMORPHIC SYNDROMES INCLUDING SOME BEHAVIOURAL PHENOTYPE SYNDROMES Christopher Gillberg, Jean Aicardi and Martin Bax5. OSSEOUS MALFORMATIONS OF THE SKULL AND CERVICAL VERTEBRAE 167PART III. NEUROLOGICAL CONSEQUENCES OF PRENATAL, PERINATAL AND EARLY POSTNATAL 183INTERFERENCE WITH BRAIN DEVELOPMENT: HYDROCEPHALUS, CEREBRAL PALSY6. HYDROCEPHALUS AND NONTRAUMATIC PERICEREBRAL COLLECTIONS 1857. CEREBRAL PALSY 210Ingeborg Krageloh-Mann and Martin BaxPART IV. METABOLIC AND HEREDODEGENERATIVE DISORDERS OF THE CENTRAL NERVOUS 243SYSTEM8. METABOLIC DISEASES 247Helene Ogier, Folker Hanefeld and Jean Aicardi9. HEREDODEGENERATIVE DISORDERS 327Jean Aicardi and Folker HanefeldPART V. POSTNATAL EXTRINSIC INSULTS 38110. INFECTIOUS DISEASES 383Cheryl Hemingway and Hermione Lyall11. PARAINFECTIOUS AND OTHER INFLAMMATORY DISORDERS OF IMMUNOLOGICAL ORIGIN 445Folker Hanefeld and Jean AicardivCONTENTS12. ACCIDENTAL AND NON-ACCIDENTAL INJURIES BY PHYSICAL AGENTS AND TOXIC AGENTS 472J Keith Brown and Robert A MinnsPART VI. TUMOURS AND VASCULAR DISORDERS 49913. TUMOURS OF THE CENTRAL NERVOUS SYSTEM AND OTHER SPACE-OCCUPYING LESIONS 50114. CEREBROVASCULAR DISORDERS 547PART VII. PAROXYSMAL DISORDERS 58115. EPILEPSY AND OTHER SEIZURE DISORDERS 583Alexis Arzimanoglou and Jean Aicardi16. PAROXYSMAL DISORDERS OTHER THAN EPILEPSY 666PART VIII. DISORDERS OF THE OCULAR,VISUAL, AUDITORY AND VESTIBULAR SYSTEMS 69717. DISORDERS OF OCULAR MOTOR AND VISUAL FUNCTIONS 699Jean Aicardi and Carey Matsuba18. HEARING AND VESTIBULAR FUNCTION 724Anne O HarePART IX. NEUROMUSCULAR DISEASES 74119. DISEASES OF THE MOTOR NEURON 74320. DISORDERS OF THE PERIPHERAL NERVES 758Robert Ouvrier and Jean Aicardi21. MUSCLE DISORDERS 801Kathryn North and Lloyd ShieldPART X. NEUROLOGICAL MANIFESTATIONS OF SYSTEMIC DISEASES 85922. ELECTROLYTE AND ACID-BASE METABOLISM DISTURBANCES, NUTRITIONAL DISORDERS AND 861OTHER SYSTEMIC DISEASESPART XI. DEVELOPMENTAL AND NEUROPSYCHIATRIC DISORDERS OF CHILDHOOD 889Christopher Gillberg23. DEVELOPMENT: NORMAL/DELAYED/DISORDERED 891Martin Bax and Christopher Gillberg24. AUTISM AND AUTISTIC-LIKE CONDITIONS 902Christopher Gillberg25. ATTENTION DEFICIT HYPERACTIVITY DISORDER AND COEXISTING IMPAIRMENTS 922Christopher GillbergINDEX 933vi"e;

"e;Diseases of the nervous system in infancy and childhood have a profound impact on the lives of patients and their families and are probably the most disruptive of all paediatric ailments. Aicardi's Diseases of the Nervous System in Childhood is thus the essential resource for child neurologists, neurologists, paediatricians, and physicians in developmental medicine. The third edition has been extensively updated to incorporate the tremendous volume of new information since the previous edition, but remains as clinically oriented as its predecessors. Because of the enormous and wide-ranging amount of new material available, Aicardi and his co-editors have been joined by an eminent team of international experts who have contributed many of the chapters.AUTHORS APPOINTMENTS page viiPREFACE ixPART I. NEONATAL NEUROLOGY 11. NEUROLOGICAL DISEASES IN THE PERINATAL PERIOD 3Linda de VriesPART II. CNS MALFORMATIONS, CHROMOSOMAL ABNORMALITIES, NEUROCUTANEOUS 39SYNDROMES AND SKULL MALFORMATIONS2. MALFORMATIONS OF THE CENTRAL NERVOUS SYSTEM 413. NEUROCUTANEOUS DISEASES AND SYNDROMES 1034. NEUROLOGICAL AND BEHAVIOURAL ASPECTS OF GENETIC ANOMALIES AND 137DYSMORPHIC SYNDROMES INCLUDING SOME BEHAVIOURAL PHENOTYPE SYNDROMES Christopher Gillberg, Jean Aicardi and Martin Bax5. OSSEOUS MALFORMATIONS OF THE SKULL AND CERVICAL VERTEBRAE 167PART III. NEUROLOGICAL CONSEQUENCES OF PRENATAL, PERINATAL AND EARLY POSTNATAL 183INTERFERENCE WITH BRAIN DEVELOPMENT: HYDROCEPHALUS, CEREBRAL PALSY6. HYDROCEPHALUS AND NONTRAUMATIC PERICEREBRAL COLLECTIONS 1857. CEREBRAL PALSY 210Ingeborg Krageloh-Mann and Martin BaxPART IV. METABOLIC AND HEREDODEGENERATIVE DISORDERS OF THE CENTRAL NERVOUS 243SYSTEM8. METABOLIC DISEASES 247Helene Ogier, Folker Hanefeld and Jean Aicardi9. HEREDODEGENERATIVE DISORDERS 327Jean Aicardi and Folker HanefeldPART V. POSTNATAL EXTRINSIC INSULTS 38110. INFECTIOUS DISEASES 383Cheryl Hemingway and Hermione Lyall11. PARAINFECTIOUS AND OTHER INFLAMMATORY DISORDERS OF IMMUNOLOGICAL ORIGIN 445Folker Hanefeld and Jean AicardivCONTENTS12. ACCIDENTAL AND NON-ACCIDENTAL INJURIES BY PHYSICAL AGENTS AND TOXIC AGENTS 472J Keith Brown and Robert A MinnsPART VI. TUMOURS AND VASCULAR DISORDERS 49913. TUMOURS OF THE CENTRAL NERVOUS SYSTEM AND OTHER SPACE-OCCUPYING LESIONS 50114. CEREBROVASCULAR DISORDERS 547PART VII. PAROXYSMAL DISORDERS 58115. EPILEPSY AND OTHER SEIZURE DISORDERS 583Alexis Arzimanoglou and Jean Aicardi16. PAROXYSMAL DISORDERS OTHER THAN EPILEPSY 666PART VIII. DISORDERS OF THE OCULAR,VISUAL, AUDITORY AND VESTIBULAR SYSTEMS 69717. DISORDERS OF OCULAR MOTOR AND VISUAL FUNCTIONS 699Jean Aicardi and Carey Matsuba18. HEARING AND VESTIBULAR FUNCTION 724Anne O HarePART IX. NEUROMUSCULAR DISEASES 74119. DISEASES OF THE MOTOR NEURON 74320. DISORDERS OF THE PERIPHERAL NERVES 758Robert Ouvrier and Jean Aicardi21. MUSCLE DISORDERS 801Kathryn North and Lloyd ShieldPART X. NEUROLOGICAL MANIFESTATIONS OF SYSTEMIC DISEASES 85922. ELECTROLYTE AND ACID-BASE METABOLISM DISTURBANCES, NUTRITIONAL DISORDERS AND 861OTHER SYSTEMIC DISEASESPART XI. DEVELOPMENTAL AND NEUROPSYCHIATRIC DISORDERS OF CHILDHOOD 889Christopher Gillberg23. DEVELOPMENT: NORMAL/DELAYED/DISORDERED 891Martin Bax and Christopher Gillberg24. AUTISM AND AUTISTIC-LIKE CONDITIONS 902Christopher Gillberg25. ATTENTION DEFICIT HYPERACTIVITY DISORDER AND COEXISTING IMPAIRMENTS 922Christopher GillbergINDEX 933vi"e;