Essential Aspects of Immunometabolism in Health and Disease
- 0 %
Der Artikel wird am Ende des Bestellprozesses zum Download zur Verfügung gestellt.

Essential Aspects of Immunometabolism in Health and Disease

 eBook
Sofort lieferbar | Lieferzeit: Sofort lieferbar I
ISBN-13:
9783030866846
Veröffentl:
2021
Einband:
eBook
Seiten:
278
Autor:
Niels Olsen Saraiva Camara
eBook Typ:
PDF
eBook Format:
Reflowable eBook
Kopierschutz:
Digital Watermark [Social-DRM]
Sprache:
Englisch
Beschreibung:

Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases.The edited volume Essentials aspects of Immunometabolism will give the readers a broad view on how metabolic pathways can influence many types of immune cells during activation, differentiation and function, in health and disease. Of note, the structure of the book was created thinking not only on the experienced immunologist but also on undergraduate and graduate students, physicians, and all members of the scientific community interested in this exciting field of research.

Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases.

The edited volume Essentials aspects of Immunometabolism will give the readers a broad view on how metabolic pathways can influence many types of immune cells during activation, differentiation and function, in health and disease. Of note, the structure of the book was created thinking not only on the experienced immunologist but also on undergraduate and graduate students, physicians, and all members of the scientific community interested in this exciting field of research.

Section 1. Introduction to Immunometabolism
Ch.1.1. Overview of Immune response
Ch.1.2. Metabolic Pathways
Ch.1.3. Mitochondrial biogenesis and dynamics in healthy and diseases
Ch.1.4. Epigenetic regulation of metabolic pathways
Ch.1.5. Metabolic pathways and cells signaling
Ch.1.6. Immunometabolism: from biochemistry to bench

Section 2. Metabolism of immune cells
Ch.2.1. Metabolic profile of innate immune cells
Ch.2.2. Metabolic profile of adaptive immune cells
Ch.2.3. Metabolism and regulation of immune response 
Ch.2.4. Metabolic sensors and immunopathology
Ch.2.5. Metabolic pathways and immune cells commitment and fate
Ch.2.6. Overlapping the immune response and cell metabolism reprograming

Section 3. Immunometabolism in health and in disease
Ch.3.1. Obesity, metabolic syndrome and inflammation
Ch.3.2. Metabolic reprogramming and cancer
Ch.3.3. Metabolic reprogramming and autoimmune diseases
Ch.3.4. Metabolic reprogramming and infectious diseases
Ch.3.5. Metabolic reprogramming and organ transplantation
Ch.3.6. Malnutrition, immune cell function and host physiology
Ch.3.7. Immune regulation of browning
Ch.3.8. Microbiota, immune response and cell metabolism interface
Ch.3.9. Physical exercise and metabolic reprogramming 
Ch.3.10. Immunotherapies targeting metabolic pathways
Ch.3.11. Immunometabolism: translating basic science into clinics

Kunden Rezensionen

Zu diesem Artikel ist noch keine Rezension vorhanden.
Helfen sie anderen Besuchern und verfassen Sie selbst eine Rezension.