Beschreibung:
Foreword; Preface; Introduction; Histopathological Diagnosis; Enzyme Histochemical Differential Diagnosis in Chronic Constipation; Functional Histopathological Differential Diagnosis in Colonic Motility Disorder; Different Colon Diseases with Chronic Constipation; Pathogenesis of Hirschsprung's Disease; 'Swiss-Roll Technique'; Intraoperative Evaluation of the Myenteric Plexus; Ultrashort Hirschsprung's Disease; Total Aganglionosis of the Colon; Hypoganglionosis of the Colon; Immaturity of the Enteric Nervous System in Childhood; Intestinal Neuronal Dysplasia Type A; Intestinal Neuronal Dysplasia Type B; Ganglioneuromatosis. Multiple Endocrine Neoplasia 2B (MEN 2B); Desmosis Coli; Architectural Malformation of the Muscularis Propria; Degenerative Leiomyopathy: A Rare Disease; Stretching Atrophy of Circular and Longitudinal Muscles in the Gut; Nerve Cell Heterotopias in Mucosa and Muscularis Propria; A Laboratory Guide to Histopathological Diagnosis of Intestinal Motility Disorders; The Most Important Technical Factors for Optimal Pathohistological Results; Recommendations for Taking Mucosal Biopsies in Chronic Constipation; Instructions for Transportation of Colorectal Biopsies or Surgical Specimens; Preparation of Cryostat Sections from Biopsies and Colorectal Specimens; The Problem of Section Thickness; Preparation of Incubation Media for Daily Routine of Enzyme Histochemical Reactions; Immunohistochemical Techniques of Paraffin Sections in the Diagnosis of Gut Dysmotility; References; Index; Abbreviations.
The symptom of chronic constipation is often caused by a series of intestinal diseases, which can be reliably diagnosed histopathologically by histochemical techniques and consequently treated by surgical intervention. The following publication is the second and completely revised edition of 'Pathology of Chronic Constipation in Pediatric and Adult Coloproctology' published in 2005, and introduces several new diseases and figures. It includes characteristics of classical and ultrashort Hirschsprung's disease as well as total intestinal aganglionosis and hypoganglionosis. New diseases such as intestinal neuronal dysplasia, desmosis coli, leiomyopathy, architectural malformation, and stretching lesions of muscularis propria are critically discussed. Atrophic desmosis is also covered. This new and frequently observed degeneration of muscularis propria in Crohn's disease, sigmoid diverticulitis, and other inflammatory intestinal diseases causes focal aperistalsis, frequently interpreted as scar stenosis. 'Histopathology of Chronic Constipation' provides a comprehensive overview of intestinal alterations which cause chronic constipation. It is therefore of special interest to diagnostic pathologists, clinicians, pediatric and abdominal surgeons, coloproctologists, and gastroenterologists.