Professor B.B. Lee began his career as a founding member of the transplant and vascular surgery program at Georgetown University, Washington, D.C., in 1979. He is now better known as a leading vascular surgeon in the field of veno-lymphatic disorders in the U.S. and a world authority on congenital vascular malformation and lymphedema. Prof. Lee, a disciple of the late David Hume of the Medical College of Virginia (Richmond, Virginia), has also made far-reaching contributions in the field of transplant surgery. During his tenure at Johns Hopkins University as clinical professor of surgery, he established a world-class living-related liver transplantation program in Seoul, Korea, as the founding professor and chairman of the Surgical Sciences Department at Samsung Medical Center and SungKyunKwan University. In recognition of his contributions to vascular surgery, Prof. Lee was named Distinguished Fellow by the Society for Vascular Surgery in the U.S. He has published over 800 original papers and abstracts in addition to more than four dozen book chapters, mainly in the field of vascular malformation and lymphedema. He has also given more than 500 lectures around the world. Prof. Lee has been serving on numerous national and international peer-reviewed journals as an editor as well as a reviewer specializing in the field of vascular malformation and lymphedema. He has played a critical role in introducing vascular malformation into the mainstream of vascular surgery. Consequently, Prof. Lee was invited by the Royal Society of Medicine and the American College of Phlebology Foundation to contribute as guest editor to a special issue of Phlebology on venous malformation in 2007. He was also invited by the American Venous Forum to write a chapter on AV malformation for the Handbook of Venous Disorders. Most notably, he was invited by the Society of Vascular Surgery/Journal of Vascular Surgery editorial board to write the vascular malformation chapter for Rutherford's Vascular Surgery, which remains the leading textbook for vascular surgeons around the world. Recently, both societies invited Prof. Lee back to write for, and update, their new editions. Prof. Lee has served as president or vice president on many national and international societies, including the IUA (International Union of Angiology) and the IUP (International Union of Phlebology). He has been elected to honorary as well as emeritus member status by numerous phlebology and lymphology societies throughout the world. For decades, he has led the IUP in addition to the IUA, boosting the image of both societies through his outstanding academic contributions. He has also successfully organized numerous world consensuses, including the consensuses on Primary Lymphedema and Venous Malformation for the IUP, in addition to the consensuses on AV malformation for the IUA. Until recently, Prof. Lee served on the ISVS (International Society of Vascular Surgery) as Vice President and also the American Specialty Board of Venous and Lymphatic Disease as a member of the Board of Directors, to promote this new specialty throughout the U.S. In 2011, Prof. Lee moved from Georgetown University to George Washington University, Washington, D.C., to provide worldwide services as the director of the Center for Vascular Malformation and Lymphedema. He also regularly contributes to the Uniformed Services University/Walter Reed Army Medical Center as Adjunct Professor and to Johns Hopkins University as Visiting Professor in addition to Georgetown University.

Dr. Stanley Rockson is the Allan and Tina Neill Professor of Lymphatic Research and Medicine at Stanford University School of Medicine. After earning his medical degree from Duke University School of Medicine, Dr Rockson completed his internship and residency training in internal medicine at Brigham and Women's Hospital of Harvard

Foreword: J. Lionel Villavicencio  

Preface:  BB Lee and Stanley Rockson 

Section I - Introduction

1.                  General Overview

Byung-Boong Lee   and Stanley G. Rockson 

2     Etiology and Classification of Lymphatic Disorders

     Stanley G. Rockson

3        Hereditary and Familial Lymphedemas

 Peter Mortimer

Section II - Embryology, Anatomy, & Histology

4. Lymphatic Vascular Development and Lymphangiogenesis

Stanley G. Rockson

5. Anatomy of the Lymphatic System and its Structural Disorders

Hiroo Suami

Section III - Physiology, Pathophysiology and Lymphodynamics          

6.  General Overview

7. Lymphodynamics

Stanley G. Rockson

8. Physiology- Lymph Flow

 David C Zawieja

9. Biomechanics of the Lymphatic Circulation

James Moore

10. Pathology & Histochemistry

Waldemar Olszewski

11. The Cellular and Molecular Composition of Lymph

Laura Santambrogio

Section IV - Clinical Diagnosis   

12.  General Overview

 Stanley G. Rockson 

13.  Clinical Staging

Sandro Michelini

The second edition of this book serves as a central source of theoretical and practical knowledge to optimize the evaluation and treatment of patients with lymphedema. The book covers all aspects of the disease from anatomical and histological features to diagnosis as well as physical/medical and surgical management of the disease.

Updated from the first edition to reflect the substantial progress in diagnostics, medical care and surgical intervention for this patient population, this volume has been reorganized to meet today's practice requirements. It addresses the challenges faced by clinicians in the management of chronic lymphedema enabling them to meet the medical needs of this large patient community.