Volume Editors:Prof. Paul T. Anastas, Dr. Bob Boethling and Prof. A. VoutchkovaPaul T. Anastas is the Teresa and H. John Heinz III Professor in the Practice of Chemistry for the Environment. He has appointments in the School of Forestry and Environmental Studies, Department of Chemistry, and Department of Chemical Engineering. In addition, Prof. Anastas serves as the Director of the Center for Green Chemistry and Green Engineering at Yale. Anastas took public service leave from Yale to serve as the Assistant Administrator for the US Environmental Protection Agency and the Agency Science Advisor from 2009-2012. From 2004 -2006, Paul Anastas served as Director of the ACS Green Chemistry Institute in Washington, D.C. He was previously the Assistant Director for the Environment in the White House Office of Science and Technology Policy where he worked from 1999-2004. Trained as a synthetic organic chemist, Dr. Anastas received his Ph.D. from Brandeis University and worked as an industrial consultant. He is credited with establishing the field of green chemistry during his time working for the U.S. Environmental Protection Agency as the Chief of the Industrial Chemistry Branch and as the Director of the U.S. Green Chemistry Program. Beside the Handbook of Green Chemistry, Dr. Anastas has published widely on topics of science through sustainability including eleven books, such as Benign by Design, Designing Safer Polymers, Green Engineering, and his seminal work with co-author John Warner, Green Chemistry: Theory and Practice.Dr. Robert (Bob) Boethling is scientist at the U.S. Environmental Protection Agency's Office of Pollution Prevention and Toxics (OPPT), Exposure Assessment Branch. He earned his Ph.D. at UCLA in 1976 and joined EPA in 1980 after a postdoctoral fellowship under Prof. Martin Alexander at Cornell University. Dr. Boethling's expertise is in biodegradation, and design and development of environmental fate data resources and estimation methods.Adelina Voutchkova is Assistant Professor at the George Washington University, Washington D.C.

The shift towards being as environmentally-friendly as possiblehas resulted in the need for this important reference on the topicof designing safer chemicals. Edited by the leading internationalexperts in the field, Robert Boethling and Adelina Votchkova, thisvolume covers such topics as toxicity, reducing hazards andbiochemical pesticides.

DESIGNING SAFER CHEMICALSThe Design of Safer Chemicals: Past, Present, and Future PerspectivesDifferential Toxicity Characterization of Green Alternative ChemicalsUnderstanding Mechanisms of Metabolic Transformations as a Tool for Designing Safer ChemicalsStructural and Toxic Mechanism-Based Approaches to Designing Safer ChemicalsInforming Substitution to Safer AlternativesDesign of Safer Chemicals - Ionic LiquidsDesigning Safer Organocatalysts - What Lessons Can Be Learned When the Rebirth of an Old Research Area Coincides with the Advent of Green Chemistry?Life-Cycle Concepts for Sustainable Use of Engineered Nanomaterials in NanoproductsDrugsGreener Chelating AgentsImprovements to the Environmental Performance of Synthetic-Based Drilling MudsBiochemical Pesticides: Green Chemistry Designs by NatureProperty-Based Approaches to Design Rules for Reduced ToxicityReducing Carcinogenicity and Mutagenicity Through Mechanism-Based Molecular Design of ChemicalsReducing EcotoxicityDesigning for Non-PersistenceReducing Physical Hazards: Encouraging Inherently Safer ProductionInteraction of Chemicals with the Endocrine System

The shift towards being as environmentally-friendly as possible has resulted in the need for this important reference on the topic of designing safer chemicals. Edited by the leading international experts in the field, this volume covers such topics as toxicity, reducing hazards and biochemical pesticides.An essential resource for anyone wishing to gain an understanding of the world of green chemistry, as well as for chemists, environmental agencies and chemical engineers.