Summarizing molecular aspects, diagnostic as well as therapeutic issues, this book is the very first and most comprehensive on hereditary aspects of tumor diseases. All the contributors have been made fellows of the Ingrid zu Solms Foundation due to their outstanding achievements in scientific research, and they discuss here the latest aspects in the diagnosis, disease management, and treatment of hereditary tumor diseases and syndromes. A must-have ready reference for medical and biology students, MDs, PhDs, physicians, and researchers.

Bis zu 10 % aller Krebserkrankungen, so schätzt man heute, sind erblich. Dieser Band behandelt erstmals molekulare Aspekte, Diagnose, therapeutische Strategien und Management vererbbarer Tumore und Syndrome im Zusammenhang. Die Autoren sind hervorragende Fachleute auf ihrem Gebiet und Stipendiaten der Ingrid-zu-Solms-Stiftung.

HEREDITARY TUMORS-GENERAL ASPECTSTumor Invasion, Progression and Metastasis (Allgayer)The Genetic Background of Hereditary Tumor Diseases (Steinlein)SYNDROMAL TYPES OF HEREDITARY TUMORSFamily Cancer Syndromes (Rehder)Genetic Dysmorphic Syndromes Leading to Tumorigenesis (Gillessen-Kaesbach)SITE-SPECIFIC HEREDITARY TUMORSHereditary Brain Tumors (Marosi)Neurofibromatosis (Wimmer, Kehrer-Sawatzki, Legius)Retinoblastoma: The Prototypic Hereditary Tumor (Dimaras, Gallie)Hereditary Cancer in the Head and Neck (Wollenberg)Hereditary Medullary and Familial Nonmedullary Thyroid Carcinoma (Weber)Lung Tumors (Danson, Teare, Woll)Hereditary Breast Cancer (Schmutzler)The Hereditary Ovarian and Endometrial Cancer (Kiechle)Prostate Cancer (Waidelich)Wilms and Rhabdoid Tumors of the Kidney (Royer-Pokora)Hereditary Renal Tumours of the Adult (Spruijt, Hoogerbrugge)Gastrointestinal Polyposis Syndromes (Friedl, Vogt)Lynch Syndrome (HNPCC) (Möslein)Gastrointestinal Stromal Tumors (GISTs) (Debiec-Rychter)Hereditary Gastric Cancer (Vogelsang, Keller)Pancreatic Cancer (Habbe, Simon)Liver Tumors (Presser)DNA-Repair Deficiency and Cancer: Lessons from Lymphoma (Chrzanowska, Digweed, Sperling, Seemanova)Leukemia (Fonatsch)Malignant Melanoma (Berking, Bosserhoff)Xeroderma Pigmentosum, Cockayne Syndrome, Trichothiodystrophy - Defects in DNA Repair and Carcinogenesis (Emmert)Hereditary Tumors in Children (Fulda)Sarcomas and Bone Tumors in Adulthood (Wardelmann)GENETIC COUNSELLING; PSYCHOONCOLOGY; AND GENERAL PERSPECTIVES FOR THERAPEUTIC STRATEGIESGenetic Counselling for Hereditary Tumors (Gadzicki, Schlegelberger)Psychooncologic Aspects of Hereditary Tumors and Predictive Testing (Neises)Molecular Targeted Therapy (Allgayer, Fulda)