Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompassing small molecule delivery, delivery of therapeutic proteins and gene delivery. The carriers surveyed include polymeric, proteinaceous and lipid systems on the nanoscale, with a focus on their adaptability for different cargoes and target tissues. Thanks to the broad coverage of carriers as well as cargoes discussed, every researcher in the field will find valuable information here.

Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompassing small molecule delivery, delivery of therapeutic proteins and gene delivery. The carriers surveyed include polymeric, proteinaceous and lipid systems on the nanoscale, with a focus on their adaptability for different cargoes and target tissues.Thanks to the broad coverage of carriers as well as cargoes discussed, every researcher in the field will find valuable information here.

PrefaceBACKBONE DEGRADABLE AND COILED-COIL BASED MACROMOLECULAR THERAPEUTICSIntroductionWater-Soluble Polymers as Carriers of Anticancer DrugsDrug-Free Macromolecular Therapeutics - A New Paradigm in Drug DeliveryGeneral Summary and OutlookDENDRITIC POLYMERS AS TARGETING NANOSCALE DRUG DELIVERY SYSTEMS FOR CANCER THERAPYIntroductionFunctional Dendritic Polymers Based Drug Delivery Vehicles for Targeting Tumor Therapy via EPR EffectTumor Targeting Moieties Functionalized Dendritic Drug Delivery Vehicles for Cancer TherapyConclusionCOMPOSITE COLLOIDAL NANOSYSTEMS FOR TARGETED DELIVERY AND SENSINGIntroductionObjectiveCellular Behavior of the CarrierApplicationsConclusionsPOLYMERIC MICELLES FOR CANCER-TARGETED DRUG DELIVERYIntroductionMicelle Formulations in Clinical DevelopmentParticle Size of MicellesMorphology of MicellesTargeting Designs of Micelles for Enhanced Accumulation and Cell InternalizationFunctional Designs of MicellesDesign of Micelles for Gene DeliveryChallenge and Future PerspectiveBIOMIMETIC POLYMERS FOR IN VIVO DRUG DELIVERYIntroductionCommonly Used Biomimetic Polymers and Their Applications in DDSChallenges and PerspectivesDRUG DELIVERY FROM PROTEIN-BASED NANOPARTICLESIntroductionPreparation and Protein-Based NanoparticlesDrug Delivery from Albumin-Based NanoparticlesDrug Delivery from Gelatine-Based NanoparticlesDrug Delivery from Other Protein-Based NanoparticlesPOLYMERIC GENE CARRIERSGene Therapy and Gene CarriersPolymeric Gene CarriersPEI Grafting Modification Polmeric Gene CarrriersLow Molecular Weight (LWM) PEI Base Polymeric Gene CarriersTargeted Shielding System for Polymeric Gene CarriersConclusionpH-SENSITIVE POLYMERIC NANOPARTICLES AS CARRIERS FOR CANCER THERAPY AND IMAGINGIntroductionpH-Sensitive PolymerspH-Sensitive Polymers as Drug CarrierspH-Sensitive Polymers for BioimagingConclusionsCHARGE-REVERSAL POLYMERS FOR BIODELIVERYApplications of Cationic Polymers in BiodeliveryBarriers for Cationic Polymers in In Vitro and In Vivo ApplicationsCharacteristic pH Gradients in Tumor Interstitium and Endo/LysosomesChemistry of Charge-Reversal Polymers Based on Acid-Labile AmidesApplications of Charge-Reversal Polymers in Biodelivery SystemsPerspectivesPHENYLBORONIC ACID-CONTAINING GLUCOSE-RESPONSIVE POLYMER MATERIALS: SYNTHESIS AND APPLICATIONS IN DRUG DELIVERYIntroductionPBA-Containing Polymers Operating Under Physiological ConditionsChemically Crosslinked PBA-Based GelsSelf-Assembled PBA-Based Polymer MicellesSelf-Assembled PBA-Based PolymersomesPerspectivesEXTRACELLULAR pH-ACTIVATED NANOCARRIERS FOR ENHANCED DRUG DELIVERY TO TUMORSIntroductionPassive and Active Tumor TargetingTargeting the Extracellular pH (pHe) in TumorsExtracellular pH-Induced Drug Delivery to TumorsLigand Exposure by a Shielding/Deshielding MethodSurface Charge Reversing NanoparticlesConclusionSTIMULATION-SENSITIVE DRUG DELIVERY SYSTEMSIntroductionpH-Sensitive Delivery SystemsThermo-Sensitive Delivery SystemsBiomolecule-Sensitive Delivery SystemsOther Environmentally Sensitive NanocarriersOutlookIndex