Beschreibung:
In light of the rapidity increasing incidence rate of bacterial and fungal infections with multi-resistant pathogens, the metabolic changes associated with host-pathogen interactions offer one of the most promising starting points for developing novel antibiotics. . Part one of this comprehensive guide describes the metabolic adaptation of pathogenic microbes in humans, while part two points to routes for the development of novel antibiotics. This is volume six of the book series on drug discovery in infectious diseases by Paul Selzer.
Dieser Werk behandelt umfassend und aktuell Stoffwechselveränderungen beim Menschen, die mit Wirt-Erreger-Beziehungen in Zusammenhang stehen. Teil 1 beschreibt die Anpassung pathogener Mikroben an Stoffwechselvorgänge. Teil 2 zeigt Wege für die Entwicklung neuartiger Antibiotika.
ADAPTION OF MICROBIAL METABOLISM IN HOST/PATHOGEN INTERACTIONMetabolic Adaption of Human Pathogenic YersiniaeCrosstalk between Metabolism and Virulence of Legionella PneumophilaMetabolism of Intracellular Salmonella EntericaThe human Microbiome in Health and DiseaseMechanisms of Dysbiosis in the Inflamed GutStrategies for Microbial Nutrient Acquisition during Infection of Rice by Magnaporthe Oryzae Introduction - Magnaporthe Oryzae Life CycleNEW INHIBITORS AND TARGETS OF INFECTIOUS DISEASESOuter Membrane Proteins as Potential Anti-Infective Drug Targets in Mannheimia HaemolyticaIdentification of Anti-Infective Compounds using AmoebaeStress Biology in Fungi and "omic"-Approaches as Suitable Tools Analyzing Plant-Microbe InteractionsTargeting Plasmids: New Ways to Plasmid CuringRegulation of Secondary Metabolism in the Grey Mould Fungus Botrytis Cinerea