The second edition of this classic text book has been completely revised, updated, and extended to include chapters on biomimetic amination reactions, Wacker oxidation, and useful domino reactions.The first-class author team with long-standing experience in practical courses on organic chemistry covers a multitude of preparative procedures of reaction types and compound classes indispensable in modern organic synthesis. Throughout, the experiments are accompanied by the theoretical and mechanistic fundamentals, while the clearly structured sub-chapters provide concise background information, retrosynthetic analysis, information on isolation and purification, analytical data as well as current literature citations. Finally, in each case the synthesis is labeled with one of three levels of difficulty.An indispensable manual for students and lecturers in chemistry, organic chemists, as well as lab technicians and chemists in the pharmaceutical and agrochemical industries.

The second edition of this classic text book has been completely revised, updated, and extended to include chapters on biomimetic amination reactions, Wacker oxidation, and useful domino reactions.The first-class author team with long-standing experience in practical courses on organic chemistry covers a multitude of preparative procedures of reaction types and compound classes indispensable in modern organic synthesis. Throughout, the experiments are accompanied by the theoretical and mechanistic fundamentals, while the clearly structured sub-chapters provide concise background information, retrosynthetic analysis, information on isolation and purification, analytical data as well as current literature citations. Finally, in each case the synthesis is labeled with one of three levels of difficulty.An indispensable manual for students and lecturers in chemistry, organic chemists, as well as lab technicians and chemists in the pharmaceutical and agrochemical industries.

C-C BOND FORMATIONNucleophilic Addition to Aldehydes, Ketones, Carboxylic Acid Derivatives (Esters, Anhydrides) and alpha,beta-Unsaturated Carbonyl Compounds; Carbonyl OlefinationAlkylation of Aldehydes/Ketones, Carboxylic Acids, and beta-Dicarbonyl CompoundsReactions of the Aldol and Mannich TypeElectrophilic and Nucleophilic AcylationReactions of Alkenes via Carbenium IonsTransition-Metal-Catalyzed ReactionsPericyclic ReactionsRadical ReactionsOXIDATION AND REDUCTIONEpoxidation of C=C BondsDihydroxylation of C=C BondsOxidation of Alcohols to Carbonyl CompoundsEnantioselective Reduction of KetonesBiomimetic Reductive AminationEnantioselective WackerHETEROCYCLIC COMPOUNDSThree- and Four-Membered HeterocyclesFive-Membered HeterocyclesSix-Membered HeterocyclesCondensed HeterocyclesOther Heterocyclic Systems; Heterocyclic DyesSELECTED NATURAL PRODUCTSIsoprenoidsCarbohydratesAmino Acids and PeptidesNucleotides and OligonucleotidesDOMINO REACTIONSDomino Reactions in Synthetic MethodologyDomino Reactions in The Synthesis of AlkaloidsDomino Reactions in The Synthesis of IsoprenoidsDomino Reactions for The Synthesis of Chromans And DioxinsDomino Reactions in The Synthesis of Chiroptical SwitchesINDEX OF REACTIONSINDEX OF PRODUCTSSUBJECT INDEX