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Frequency of ANCA in glomerulonephritis.
University of Health sciences, Lahore, Pakistan
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Gewicht:
107 g
Format:
220x150x4 mm
Beschreibung:
I have graduation in medical technology from Punjab University, Lahore & my masters program in medical technology from University of Health Sciences, Lahore. Now I am doing MPhil in biochemistry from National University of Science & Technology, Lahore.
Objectives: Current study was designed to determine the frequency of ANCA (p-ANCA and c-ANCA) in clinically diagnosed glomerulonephritis patients. Study Design: Cross-sectional analytical study. Place and Period of study: Department of Immunology, University of Health Sciences, Lahore in a period of one year. Materials and Methods: The study included 64 glomerulonephritis patients. Methodology: Levels of ANCA (MPO and PR3) were determined by ELISA technique. Results: Four (6.25%) patients showed positive reaction to myeloperoxidase [MPO] antigen while 1 (1.56%) was positive for proteinase-3 [PR3] antigen. Sero-positivity for MPO and PR3 in the patients of 40-60 years of age,was 14% and 3.6% respectively. p-value for MPO and PR3 was 0.05 and