Biology of C Reactive Protein in Health and Disease

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Gewicht:
906 g
Format:
260x183x23 mm
Beschreibung:

Waliza Ansar. PhD is an alumnus of the erstwhile Presidency College, Kolkata. She mastered in Zoology with specialization in Fisheries and Aquaculture from Calcutta University. With interest in the field of immunology, she started her research in 2003 in Indian Institute of Chemical Biology, Kolkata and earned her Ph.D degree working on various biological roles of CRP in Malaria, Leishmania and Tuberculosis. After her post-doctoral research in IICB working on host-parasite interactions, she started her teaching career as a Lecturer of Zoology in Presidency College, Kolkata in 2002. In 2009 she joined Asutosh College, Kolkata as a lecturer of Zoology for postgraduate students. Currently, she is working as an Assistant Professor of Zoology, Behala College, Kolkata, under Calcutta University. Her current research interest involves various clinical role of CRP in diseases, pathophysiology of some acute diseases, nanotechnology and therapeutic applications and stem cell therapy. She has presented her work in international and national symposiums. She has published a number of papers in journals of national and international repute. She also has authored a number of publications and book chapters.

The first book that details the role of CRP in biology and physiology of normal and disease condition
1. Immune System: Freedom from the burden of diseases.- 2. CRP: Historical perspective, structure, evolution, synthesis, clinical and biological functions.- 3. Acute-Phase response and Acute Phase Proteins: Application in Human and Veterinary clinical chemistry.- 4. Inflammation, inflammatory diseases, markers and mediators: Role of CRP in some inflammatory diseases.- 5. Micro-heterogeneity of Proteins: Role in diseases.- 6. Pathobiological role of CRP in some diseases: Clinical medical applications of CRP.- 7. Role of CRP in cardiovascular diseases.- 8. Role of CRP in Leishmaniasis.- 9. CRP and diabetes: Sugar is not so sweet.- 10. CRP and Cancer.- 11. Role of CRP in Malaria.

This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution. Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, rheumatoid arthritis and infectious diseases and others. It also discusses the role of innate immunity and acute phase response (APR) and their key mediators in the host body in response to tissue injury, infection, trauma or surgery, immunological disorders or neoplastic growth. CRP's significance in inflammation is highlighted, and its importance as a clinical marker in cardiovascular disease, its functional significance in Leishmania and Plasmodium infections, its association with the development of insulin resistance in type 2 diabetes mellitus, and its role in cancer are discussed in detail. The book also includes clinical data studies and presents the latest research advances to further readers' understanding of CRP.

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