Introduction. Nanotechnologies and the quest for responsibility; Simone Arnaldi, Arianna Ferrari, Paolo Magaudda, Francesca Marin.- Part 1 Scrutinizing responsibility. Theoretical explorations into an entangled concept.- Responsibility and visions in the new and emerging technologies; Arianna Ferrari, Francesca Marin.- Features of intergenerational moral responsibility in the age of the emerging technologies; Silvia Zullo.- The Role of responsible stewardship in nanotechnology and synthetic biology; Ilaria Anna Colussi.- Part 2 Technology assessment and public engagement.- Technology assessment beyond toxicology - the case of nanomaterials; Torsten Fleischer, Jutta Jahnel, Stefanie B. Seitz.- Ethics Research Committees in reviewing nanotechnology clinical trials protocol; Viviana Daloiso, Antonio G. Spagnolo.-Governance of Nanotechnology: engagement and public participation; Giuseppe Pellegrini.- Part 3 Representations and arrangements of responsibility.- Value chain responsibility in emerging technologies; Colette Bos, Harro van Lente.- On being responsible: Multiplicity in responsible development; Sarah R. Davies, Cecilie Glerup, Maja Horst.- Nanotechnology and configurations of responsibilities in boundary organizations; Paolo Magaudda.- Who is responsible? Nanotechnology and responsibility in the Italian daily press; Simone Arnaldi.- Epilogue: Nanotechnology beyond nanotechnologies Responsible Research and Innovation: an emerging issue in research policy rooted in the debate on nanotechnology; Armin Grunwald.- Index.