Drug Discovery and Development
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Drug Discovery and Development

From Targets and Molecules to Medicines
 eBook
Sofort lieferbar | Lieferzeit: Sofort lieferbar I
ISBN-13:
9789811555343
Veröffentl:
2021
Einband:
eBook
Seiten:
522
Autor:
Ramarao Poduri
eBook Typ:
PDF
eBook Format:
Reflowable eBook
Kopierschutz:
Digital Watermark [Social-DRM]
Sprache:
Englisch
Beschreibung:

This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.

This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing.

Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.


Chapter 1: Historical Perspective of Drug Discovery and Development.- Chapter2: Natural Products and Drug Discovery.- Chapter 3: The Concept Of Receptors And Molecules Interaction In Drug  Discovery And Development.- Chapter 4: Chemical Structure and Stereochemistry.- Chapter 5:Biased Agonism:Renewing GPCR's targetability.- Chapter 6: Computer Aided Drug Discovery.- Chapter 7: Pharmacological screening of novel chemical entities.- Chapter 8:Drug Target Identification and Validation.- Chapter 9: Genetics and Drug Discovery.- Chapter 10: Stem Cells and Therapeutics.- Chapter 11: Pharmacokinetics.- Chapter 12: Regulatory Toxicological Testing.- Chapter 13: Nanotoxicology and Regulatory Requirements.- Chapter 14: Clinical Trials in Industrial Drug Development.- Chapter 15:Pharmacovigilance.- Chapter 16: Regulatory Process for New Drug Approval in India.- Chapter 17: Pharma Industry, Academia, Regulatory Authorities, and End-user Interaction.- Chapter 18: Statistics.

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