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Autor: Matthias Egger
ISBN-13: 9780470693148
Einband: E-Book
Seiten: 512
Sprache: Englisch
eBook Typ: PDF
eBook Format: E-Book
Kopierschutz: Adobe DRM [Hard-DRM]
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Systematic Reviews in Health Care

Meta-Analysis in Context
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The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.
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Foreword.
Introduction:.

Rationale, potentials and promise of systematic review.

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Part I: Systematic reviews of controlled trials.

Principles and procedures.

Problems and limitations.

Identifying randomised trials.

Assessing the quality of controlled clinical trials.

Obtaining individual patient data from randomised controlledtrials.

Assessing the quality of reports of systematic reviews.

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Part II: Investigating variability within and betweenstudies.

Going beyond the grand mean.

Why and how sources of heterogeneity should be investigated.

Analysing the relationship between treatment benefit andunderlying risk.

Investigating and dealing with publication and other biases.

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Part III: Systematic review of observational studies.

Systematic reviews of observational studies.

Systematic reviews of prognostic studies.

Systematic reviews of evaluations of diagnostic studies.

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Part IV: Statistical method and computer software.

Statistical methods of examining heterogeneity and combiningresults from several studies.

Choice of effect measure for binary outcomes.

Meta-analysis software.

Meta-analysis in STATA.

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Part V: Using systematic reviews in practice.

Applying the results of systematic reviews at the bedside.

Numbers needed to treat derived from meta-analysis: pitfalls andcautions.

Using systematic reviews in clinical guidelines development.

Using systematic reviews for evidence based policy making.

Using systematic reviews for economic evaluation.

Using systematic reviews and registers of ongoing trials forscientific and ethical trial design.

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Part VI: The Cochrane Collaboration.

The Cochrane Collaboration in the 20th Century.

The Cochrane Collaboration in the 21st Century: ten challengesand one reason whey they must be met.

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Part VII: Future challenges.

Unresolved issues and future developments

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Autor: Matthias Egger
ISBN-13 :: 9780470693148
ISBN: 0470693142
Verlag: John Wiley & Sons
Seiten: 512
Sprache: Englisch
Auflage 2, 2. Auflage
Sonstiges: Ebook